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Chemical probes are specific small molecules used in biological research to investigate the function and behavior of biomolecules within cells or organisms. These probes are designed to interact with their target molecules in a highly selective and often reversible manner, enabling researchers to modulate the activity of the target and study its biological effects. It is a gateway to understanding fundamental biological processes, aiding in developing first-in-class drugs.
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CAS#:
1355326-35-0
Name:
Target:
Isocitrate dehydrogenase [NADP] cytoplasmic (R132H) | pX = 7.15
doi
Properties:
MW:
462.243
|
cLogP:
4.719
$53/5 mg
(EBC)
1
CAS#:
1609392-27-9
Name:
Target:
Non-receptor tyrosine-protein kinase TYK2 | pX = 9.7
Target action:
Radioligand (/ligand)
doi
Properties:
MW:
425.459
|
cLogP:
2.032
$50/5 mg
(EBC)
1
CAS#:
2166387-64-8
Name:
Target:
B-cell lymphoma 6 protein | pX = 7.14
Target action:
Inhibitor
doi
Properties:
MW:
557.215
|
cLogP:
0.599
$484/5 mg
(EBC)
1
CAS#:
1793053-37-8
Name:
Target:
N-lysine methyltransferase SMYD2 | pX = 7.82
Target action:
Inhibitor
doi
Properties:
MW:
574.342
|
cLogP:
6.859
$186/5 mg
(EBC)
1
CAS#:
2230836-55-0
Name:
Target:
Son of sevenless homolog 1 | pX = 8.3
Target action:
Inhibitor
doi
Properties:
MW:
462.465
|
cLogP:
4.461
$184/5 mg
(EBC)
1
CAS#:
1599477-75-4
Name:
Target:
Free fatty acid receptor 4 | pX = 7.48
Target action:
Agonist
doi
Properties:
MW:
405.839
|
cLogP:
6.063
$89/5 mg
(EBC)
1
CAS#:
1009820-21-6
Name:
Target:
Casein kinase II subunit alpha | pX = 9.42
doi
Properties:
MW:
349.77
|
cLogP:
5.592
$85/5 mg
(EBC)
1
CAS#:
50-24-8
Name:
Target:
Glucocorticoid receptor | pX = 8.59
Target action:
Agonist
doi
Properties:
MW:
360.444
|
cLogP:
1.423
$19/5 mg
(EBC)
1
CAS#:
2229036-62-6
Name:
Target:
ALK tyrosine kinase receptor | pX = 7.72
Target action:
Radioligand (/ligand)
doi
Properties:
MW:
913.335
|
cLogP:
7.17
$277/5 mg
(EBC)
1
CAS#:
1404456-53-6
Name:
Target:
Protein phosphatase 1D | pX = 8.46
Target action:
Inhibitor
doi
Properties:
MW:
460.17
|
cLogP:
4.593
$43/5 mg
(EBC)
1
CAS#:
1202757-89-8
Name:
Target:
Tyrosine-protein kinase BTK | pX = 12
Target action:
Inhibitor
doi
Properties:
MW:
423.171
|
cLogP:
4.554
$67/5 mg
(EBC)
1
CAS#:
1454555-29-3
Name:
Target:
AP2-associated protein kinase 1 | pX = 8.5
Target action:
Inhibitor
doi
Properties:
MW:
396.443
|
cLogP:
2.68
$96/5 mg
(EBC)
1
CAS#:
1232416-25-9
Name:
Target:
Serine/threonine-protein kinase ATR | pX = 9.78
Target action:
Inhibitor
doi
Properties:
MW:
463.168
|
cLogP:
3.028
$89/5 mg
(EBC)
1
CAS#:
1257044-40-8
Name:
Target:
Apoptosis regulator, Bcl-2 | pX = 10
doi
Properties:
MW:
868.439
|
cLogP:
10.312
$19/5 mg
(EBC)
1
CAS#:
1161205-04-4
Name:
Target:
Metabotropic glutamate receptor 4 | pX = 6.96
Target action:
Modulator
doi
Properties:
MW:
262.692
|
cLogP:
2.8
$78/5 mg
(EBC)
1
CAS#:
1783816-74-9
Name:
Target:
Serine/threonine-protein kinase PAK 1 | pX = 8.3
Target action:
Inhibitor
doi
Properties:
MW:
479.17
|
cLogP:
7.059
$164/5 mg
(EBC)
1
CAS#:
1542705-92-9
Name:
Target:
Transitional endoplasmic reticulum ATPase | pX = 7.96
Target action:
Inhibitor
doi
Properties:
MW:
413.472
|
cLogP:
3.302
$150/5 mg
(EBC)
1
CAS#:
1358575-02-6
Name:
Target:
Probable G-protein coupled receptor 52 | pX = 7.15
Target action:
Agonist
doi
Properties:
MW:
392.35
|
cLogP:
3.2
$120/5 mg
(EBC)
1
CAS#:
1291779-76-4
Name:
Target:
fatty acid synthase | pX = 7.1
doi
Properties:
MW:
391.463
|
cLogP:
3.084
$185/5 mg
(EBC)
1
CAS#:
1229705-06-9
Name:
Target:
E3 ubiquitin-protein ligase Mdm2 | pX = 8.22
Target action:
Inhibitor
doi
Properties:
MW:
616.482
|
cLogP:
4.966
$53/5 mg
(EBC)
1
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