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Chemical probes are specific small molecules used in biological research to investigate the function and behavior of biomolecules within cells or organisms. These probes are designed to interact with their target molecules in a highly selective and often reversible manner, enabling researchers to modulate the activity of the target and study its biological effects. It is a gateway to understanding fundamental biological processes, aiding in developing first-in-class drugs.
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CAS#:
2001571-40-8
Name:
Target:
Serine/threonine-protein kinase mTOR | pX = 7.82
Target action:
Inhibitor
doi
Properties:
MW:
383.171
|
cLogP:
1.087
$870/5 mg
(EBC)
1
CAS#:
935693-62-2
Name:
Target:
Histone-lysine N-methyltransferase EHMT1 | pX = 8.72
doi
Properties:
MW:
490.306
|
cLogP:
4.756
$84/5 mg
(EBC)
1
CAS#:
1392494-64-2
Name:
Target:
Potassium voltage-gated channel subfamily S member 1 | pX = 7.16
doi
Properties:
MW:
308.189
|
cLogP:
3.816
$480/5 mg
(EBC)
1
CAS#:
1374640-70-6
Name:
Target:
Epidermal growth factor receptor (L858R/T790M) | pX = 8.15
Target action:
Inhibitor
doi
Properties:
MW:
555.221
|
cLogP:
4.511
$53/5 mg
(EBC)
1
CAS#:
33069-62-4
Name:
Target:
Tubulin | pX = 9.3
Target action:
Inhibitor
doi
Properties:
MW:
853.906
|
cLogP:
4.731
$43/5 mg
(EBC)
1
CAS#:
1773489-72-7
Name:
Target:
Nuclear receptor coactivator 1 | pX = 8.15
Target action:
Agonist
doi
Properties:
MW:
487.13
|
cLogP:
5.358
$250/5 mg
(EBC)
1
CAS#:
1860875-51-9
Name:
Target:
Protein cereblon | pX = 8.38
Target action:
Radioligand (/ligand)
doi
Properties:
MW:
461.846
|
cLogP:
2.44
$480/5 mg
(EBC)
1
CAS#:
1170613-55-4
Name:
Target:
Transient receptor potential cation channel subfamily A member 1 | pX = 7.17
Target action:
Inhibitor
doi
Properties:
MW:
207.106
|
cLogP:
3.536
$120/5 mg
(EBC)
1
CAS#:
1236109-67-3
Name:
Target:
Free fatty acid receptor 1 | pX = 7.72
Target action:
Agonist
doi
Properties:
MW:
345.173
|
cLogP:
4.937
$82/5 mg
(EBC)
1
CAS#:
70006-24-5
Name:
Target:
Dopamine 4 receptor variant D4.4 | pX = 7.91
Target action:
Agonist
doi
Properties:
MW:
293.366
|
cLogP:
2.356
$71/5 mg
(EBC)
1
CAS#:
1351758-81-0
Name:
Target:
Leucine-rich repeat serine/threonine-protein kinase 2 | pX = 7.69
doi
Properties:
MW:
377.825
|
cLogP:
2.739
$150/5 mg
(EBC)
1
CAS#:
658084-64-1
Name:
Target:
Nicotinamide phosphoribosyltransferase | pX = 9.52
Target action:
Radioligand (/ligand)
doi
Properties:
MW:
391.226
|
cLogP:
2.991
$120/5 mg
(EBC)
1
CAS#:
901245-65-6
Name:
Target:
Peregrin | pX = 7.1
Target action:
Inhibitor
doi
Properties:
MW:
394.467
|
cLogP:
2.937
$82/5 mg
(EBC)
1
CAS#:
1197953-54-0
Name:
Target:
epidermal growth factor receptor | pX = 9.09
Target action:
Inhibitor
doi
Properties:
MW:
583.259
|
cLogP:
2.024
$55/5 mg
(EBC)
1
CAS#:
2650530-00-8
Name:
Target:
Serine/threonine-protein kinase 17B | pX = 7.47
Target action:
Inhibitor
doi
Properties:
MW:
358.458
|
cLogP:
4.83
$127/5 mg
(EBC)
1
CAS#:
2366268-80-4
Name:
Target:
Cyclin-dependent kinase 6 | pX = 8.1
Target action:
Inhibitor
doi
Properties:
MW:
871.388
|
cLogP:
2.619
$568/5 mg
(EBC)
1
CAS#:
1920084-32-7
Name:
Target:
melatonin receptor type 1a | pX = 8.2
Target action:
Radioligand (/ligand)
doi
Properties:
MW:
292.021
|
cLogP:
3.486
$89/5 mg
(EBC)
1
CAS#:
1649450-12-3
Name:
Target:
High affinity choline transporter 1 | pX = 7.14
Target action:
Inhibitor
doi
Properties:
MW:
387.473
|
cLogP:
1.772
$85/5 mg
(EBC)
1
CAS#:
2326521-71-3
Name:
Target:
GTPase KRas (G12D) | pX = 12
Target action:
Inhibitor
doi
Properties:
MW:
604.117
|
cLogP:
5.78
$41/5 mg
(EBC)
1
CAS#:
2227549-00-8
Name:
Target:
Solute carrier family 13 member 5 | pX = 7.31
Target action:
Inhibitor
doi
Properties:
MW:
445.335
|
cLogP:
3.726
$41/5 mg
(EBC)
1
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