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EBCL-0027
FDA (U.S. Food and Drug Administration in the USA), EMA (European Medicines Agency in the European Union), NMPA (National Medical Products Administration in China), and PMDA (Pharmaceuticals and Medical Devices Agency in Japan) are major regulatory agencies ensuring the safety and efficacy of human drugs.
The library of Approved Drugs is composed of 1144 compounds certified by one or few leading pharmaceutical regulatory agencies.
Related terms: H1 receptor, D2 receptor, carbonic anhydrase, 5-HT2A receptor, acetylcholinesterase, COX-1, epidermal growth factor receptor, COX-2, D3 receptor
Avanafil is a potent and highly selective phosphodiesterase-5 (PDE-5) inhibitor. It is used to treat erectile dysfunction
Melperone is an atypical antipsychotic that demonstrates antagonist activity at D 2 dopaminergic and 5-HT 2A serotonergic receptors
Osalmid is a ribonucleotide reductase small subunit M2 targeting compound
Lornoxicam is a non-steroidal anti-inflammatory drug (NSAID). It potently inhibits both COX-1 and COX-2.
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NoteAll the compounds with solubility below 10 mM are shipped as 2 mM solutions.
H1 receptor
39
39
Number of compounds
39
D2 receptor
31
31
Number of compounds
31
COX-1
29
29
Number of compounds
29
carbonic anhydrase 2
26
26
Number of compounds
26
Kv11.1
24
24
Number of compounds
24
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