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EBCL-0053

Antiviral Compounds

Antiviral agents play a critical role in combating viral infections, which can disrupt the body’s defense and lead to a wide range of diseases, from acute illnesses to chronic conditions. Compiled using the latest data from authoritative sources, Library of Antiviral Compounds includes compounds targeting essential viral proteins. It features inhibitors of viral entry, replication, transcription, translation, and assembly, as well as molecules that interfere with host-virus interactions crucial for viral survival and propagation.

The library encompasses both approved antiviral drugs and investigational compounds with known biological activity against various viral families, including RNA viruses (e.g., coronaviruses, influenza viruses) and DNA viruses (e.g., herpesviruses, papillomaviruses). Each molecule is carefully annotated with its mechanism of action, target specificity, and therapeutic relevance, providing a rich resource for the study of viral biology and therapeutic intervention.

This comprehensive library consists of 842 compounds and supports research in antiviral drug discovery, focusing on diverse viral targets and pathways to develop novel therapeutics. Detailed annotations facilitate the understanding of molecular interactions with viral and host targets, aiding in the identification of biomarkers for viral infection, disease progression, and treatment response.


Related terms: antivirals, HIV, herpes, hepatitis, SARS, coronavirus, influenza

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Preplated options

Dry powder/solution (DMSO)Dry powder
Number of compounds842
Comment

Highlights

Molecule highlight
EBC-58076CAS: 1190307-88-0

Sofosbuvir is a direct-acting antiviral agent used to treat specific hepatitis C virus (HCV)

Molecule highlight
EBC-14802CAS: 188062-50-2

Abacavir is an antiviral agent used in HIV treatment

Molecule highlight
EBC-03876CAS: 204255-11-8

Oseltamivir is a medication employed in preventing anf treatment of influenza

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Disclaimer

All our products are for research purpose only. Any personal or non-scientific use is strictly prohibited.

Note

All the compounds with solubility below 10 mM are shipped as 2 mM solutions.

Product Features

Product Features:

  • A set of 842 Antiviral relevant molecules with sub-10 micromolar activity coefficients values for HTS/HCS programs.
  • Calculated structural diversity of the collection: 0.87
  • Comprehensive documentation with structures, trivial names, activity coefficients values, types of action on target and references to original literature.
  • NMR and LCMS validated purity.
  • All the compounds are available in stock for hit follow-up.
  • The library is continuously updated

Product Details

  • Format: 10 - 100 µL of 10 mM DMSO stock solutions; dry powders (1 mg);
  • Container: 384-well microplates;
  • Storage: - 18 °C;
  • Shipping: Dry ice.

Utility

  • High throughput screening (HTS);
  • High content screening (HCS);
  • Cherry picking.