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Antiviral agents play a critical role in combating viral infections, which can disrupt the body’s defense and lead to a wide range of diseases, from acute illnesses to chronic conditions. Compiled using the latest data from authoritative sources, Library of Antiviral Compounds includes compounds targeting essential viral proteins. It features inhibitors of viral entry, replication, transcription, translation, and assembly, as well as molecules that interfere with host-virus interactions crucial for viral survival and propagation.
The library encompasses both approved antiviral drugs and investigational compounds with known biological activity against various viral families, including RNA viruses (e.g., coronaviruses, influenza viruses) and DNA viruses (e.g., herpesviruses, papillomaviruses). Each molecule is carefully annotated with its mechanism of action, target specificity, and therapeutic relevance, providing a rich resource for the study of viral biology and therapeutic intervention.
This comprehensive library consists of 842 compounds and supports research in antiviral drug discovery, focusing on diverse viral targets and pathways to develop novel therapeutics. Detailed annotations facilitate the understanding of molecular interactions with viral and host targets, aiding in the identification of biomarkers for viral infection, disease progression, and treatment response.
Related terms: antivirals, HIV, herpes, hepatitis, SARS, coronavirus, influenza
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NoteAll the compounds with solubility below 10 mM are shipped as 2 mM solutions.
Human immunodeficiency virus 1
96
96
Number of compounds
96
Hepatitis C virus
62
62
Number of compounds
62
Haemophilus influenzae
44
44
Number of compounds
44
Human immunodeficiency virus
40
40
Number of compounds
40
RNA-directed DNA polymerase
40
40
Number of compounds
40
Human alphaherpesvirus 1
35
35
Number of compounds
35
main protease
35
35
Number of compounds
35
Integrase (peptide)
34
34
Number of compounds
34
Human immunodeficiency virus 1 (strain IIB)
30
30
Number of compounds
30
Hepatitis B virus
26
26
Number of compounds
26
Hemagglutinin
22
22
Number of compounds
22
Coxsackievirus B3
21
21
Number of compounds
21
Human respiratory syncytial virus LONG
20
20
Number of compounds
20
Integrase - Pc4 And Sfrs1 Interacting Protein 1 Complex
19
19
Number of compounds
19
Hepatitis C virus subtype 1b
19
19
Number of compounds
19
RNA-directed RNA polymerase
18
18
Number of compounds
18
Human immunodeficiency virus 1 (strain IIIb)
18
18
Number of compounds
18
DNA polymerase (Epsilon)
17
17
Number of compounds
17
Angiopoietin-1 receptor
17
17
Number of compounds
17
ALK tyrosine kinase receptor
17
17
Number of compounds
17
Vaccinia virus
16
16
Number of compounds
16
Herpes simplex virus 2
16
16
Number of compounds
16
Coxsackievirus A21
16
16
Number of compounds
16
Protease
15
15
Number of compounds
15
Human immunodeficiency virus 1 (strain 93IN101)
15
15
Number of compounds
15
EBCL-0053