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The Library of Bioactive Compounds Max is our most extensive collection, featuring 14388 compounds with known biological activity, including a diverse range of drug candidates, tool compounds, metabolites, prodrugs, and approved drugs.
Each compound is fully annotated with detailed biological activity data and supported by literature references, ensuring comprehensive and up-to-date information.We also offer custom synthesis and compound sourcing, allowing access to nearly any compound through our in-house capabilities, making this library an invaluable resource for drug discovery, repurposing, and research applications.
Related Terms: bioactivity, biological targeting, GPCR, carbonic anhydrase, ligand-gated ion channel.
This compound is an inhibitor of Farnesoid X receptor.
This compound is an inhibitor of poly polymerase 1.
CBA is a potent and selective inhibitor of the cation channel TRPM4, with an IC50 of 1.1 μM.
This compound inhibits acetylcholinesterase and carbonic anhydrases CA II and CA I.
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All our products are for research purpose only. Any personal or non-scientific use is strictly prohibited.
NoteAll the compounds with solubility below 10 mM are shipped as 2 mM solutions.
Library of Bioactive Compounds Max is a set of 14388 bioactive molecules for HTS/HCS programs.
The Library of Bioactive Compounds Max covers novel promising preclinical lead compounds, clinical candidates and approved drugs.
Calculated structural diversity of the collection: 0.87.
Comprehensive documentation with structures, trivial names, synonyms, activity coefficient values, types of action on target and references to original literature.
NMR and LCMS validated purity.All the compounds are available in stock for hit follow-up.
The library is continuously updated.
Others
777
777
Number of compounds
777
Carbonic anhydrases
387
387
Number of compounds
387
Oxidoreductases
309
309
Number of compounds
309
Prostaglandin synthases
187
187
Number of compounds
187
Acetylcholine turnover
184
184
Number of compounds
184
5-Hydroxytryptamine receptors
178
178
Number of compounds
178
Catecholamine turnover
164
164
Number of compounds
164
Adenosine receptors
163
163
Number of compounds
163
Dopamine receptors
138
138
Number of compounds
138
Hydrolases
137
137
Number of compounds
137
CYP2 family: drug metabolising subset
137
137
Number of compounds
137
3C. 3-Ketosteroid receptors
136
136
Number of compounds
136
Adrenoceptors
130
130
Number of compounds
130
Histone deacetylases (HDACs)
110
110
Number of compounds
110
Ionotropic glutamate receptors
109
109
Number of compounds
109
Bromodomain kinase (BRDK) family
102
102
Number of compounds
102
Voltage-gated potassium channels (Kv)
101
101
Number of compounds
101
Transient Receptor Potential channels (TRP)
96
96
Number of compounds
96
"Phosphodiesterases, 3',5'-cyclic nucleotide (PDEs)"
94
94
Number of compounds
94
Nicotinic acetylcholine receptors (nACh)
86
86
Number of compounds
86
Metabotropic glutamate receptors
82
82
Number of compounds
82
Monoamine transporter subfamily
77
77
Number of compounds
77
Histamine receptors
76
76
Number of compounds
76
CYP1 family
73
73
Number of compounds
73
Voltage-gated sodium channels (NaV)
67
67
Number of compounds
67
Acetylcholine receptors (muscarinic)
63
63
Number of compounds
63
Nitric oxide synthases
60
60
Number of compounds
60
Class A Orphans
59
59
Number of compounds
59
M24: Methionyl aminopeptidase
58
58
Number of compounds
58
Lipoxygenases
57
57
Number of compounds
57
"CYP11, CYP17, CYP19, CYP20 and CYP21 families"
57
57
Number of compounds
57
CFTR
56
56
Number of compounds
56
Cannabinoid receptors
53
53
Number of compounds
53
E3 ubiquitin ligase components
51
51
Number of compounds
51
Dioxygenases
51
51
Number of compounds
51
Protein arginine N-methyltransferases
47
47
Number of compounds
47
"Type III RTKs: PDGFR, CSFR, Kit, FLT3 receptor family"
47
47
Number of compounds
47
Receptor tyrosine phosphatase (RTP) family
47
47
Number of compounds
47
GABAA receptors
47
47
Number of compounds
47
Janus kinase (JakA) family
46
46
Number of compounds
46
S1: Chymotrypsin
44
44
Number of compounds
44
p38 subfamily
43
43
Number of compounds
43
S9: Prolyl oligopeptidase
42
42
Number of compounds
42
GSK subfamily
42
42
Number of compounds
42
Free fatty acid receptors
40
40
Number of compounds
40
Poly ADP-ribose polymerases
38
38
Number of compounds
38
Type I RTKs: ErbB (epidermal growth factor) receptor family
37
37
Number of compounds
37
Opioid receptors
37
37
Number of compounds
37
M10: Matrix metallopeptidase
37
37
Number of compounds
37
Histone demethylases
37
37
Number of compounds
37
P2X receptors
36
36
Number of compounds
36
3A. Estrogen receptors
36
36
Number of compounds
36
Voltage-gated calcium channels (CaV)
34
34
Number of compounds
34
Type V RTKs: FGF (fibroblast growth factor) receptor family
34
34
Number of compounds
34
Blood coagulation components
33
33
Number of compounds
33
C1: Papain
32
32
Number of compounds
32
Hydroxycarboxylic acid receptors
29
29
Number of compounds
29
Trace amine receptor
28
28
Number of compounds
28
DNA topoisomerases
28
28
Number of compounds
28
Glycosidases
26
26
Number of compounds
26
Chemokine receptors
26
26
Number of compounds
26
Abl family
25
25
Number of compounds
25
Casein kinase 1 (CK1) family
25
25
Number of compounds
25
1C. Peroxisome proliferator-activated receptors
24
24
Number of compounds
24
Orphan or poorly characterized SLC22 family members
24
24
Number of compounds
24
IKK family
24
24
Number of compounds
24
SLC40 iron transporter
24
24
Number of compounds
24
Leucine-rich repeat kinase (LRRK) family
23
23
Number of compounds
23
TAK1 subfamily
23
23
Number of compounds
23
Glycine transporter subfamily
23
23
Number of compounds
23
Rho kinase
22
22
Number of compounds
22
NOD-like receptor family
22
22
Number of compounds
22
Prolyl hydroxylases
21
21
Number of compounds
21
JNK subfamily
21
21
Number of compounds
21
Src family
21
21
Number of compounds
21
Interleukin-1 receptor-associated kinase (IRAK) family
21
21
Number of compounds
21
Fak family
21
21
Number of compounds
21
Non-enzymatic BRD containing proteins
20
20
Number of compounds
20
ABCG subfamily
20
20
Number of compounds
20
RAF family
20
20
Number of compounds
20
Melatonin receptors
19
19
Number of compounds
19
Dyrk1 subfamily
19
19
Number of compounds
19
1H. Liver X receptor-like receptors
19
19
Number of compounds
19
Polo-like kinase (PLK) family
19
19
Number of compounds
19
Tec family
19
19
Number of compounds
19
1I. Vitamin D receptor-like receptors
19
19
Number of compounds
19
Tachykinin receptors
19
19
Number of compounds
19
Aurora kinase (Aur) family
19
19
Number of compounds
19
C44: Phosphoribosyl pyrophosphate amidotransferase
18
18
Number of compounds
18
Histone methyltransferases (HMTs)
18
18
Number of compounds
18
Casein kinase 2 (CK2) family
18
18
Number of compounds
18
IRE family
18
18
Number of compounds
18
Taste 1 receptors
17
17
Number of compounds
17
2-Acylglycerol ester turnover
17
17
Number of compounds
17
ABCC subfamily
17
17
Number of compounds
17
Prostanoid receptors
16
16
Number of compounds
16
MKN subfamily
16
16
Number of compounds
16
CDK4 subfamily
16
16
Number of compounds
16
Transglutaminases
16
16
Number of compounds
16
PIM family
16
16
Number of compounds
16
Pyruvate kinases (EC 2.7.1.40)
15
15
Number of compounds
15
Inwardly rectifying potassium channels (KIR)
15
15
Number of compounds
15
Histone acetyltransferases (HATs)
15
15
Number of compounds
15
Angiotensin receptors
15
15
Number of compounds
15
C48: Ulp1 endopeptidase
15
15
Number of compounds
15
ABCB subfamily
15
15
Number of compounds
15
Glycine receptors
15
15
Number of compounds
15
Receptor interacting protein kinase (RIPK) family
14
14
Number of compounds
14
Transthyretin
14
14
Number of compounds
14
1F. Retinoic acid-related orphans
14
14
Number of compounds
14
A1: Pepsin
14
14
Number of compounds
14
"Phosphatidylinositol-4,5-bisphosphate 3-kinase family"
14
14
Number of compounds
14
Sigma receptors
13
13
Number of compounds
13
Two-pore domain potassium channels (K2P)
13
13
Number of compounds
13
"Calcium- and sodium-activated potassium channels (KCa, KNa)"
13
13
Number of compounds
13
Lanosterol biosynthesis pathway
13
13
Number of compounds
13
Lysophospholipid (S1P) receptors
13
13
Number of compounds
13
GABAB receptors
13
13
Number of compounds
13
ERK subfamily
13
13
Number of compounds
13
M28: Aminopeptidase Y
12
12
Number of compounds
12
"CYP39, CYP46 and CYP51 families"
12
12
Number of compounds
12
STAT transcription factors
12
12
Number of compounds
12
Basic leucine zipper domain TFs
12
12
Number of compounds
12
GABA transporter subfamily
12
12
Number of compounds
12
Bile acid receptor
12
12
Number of compounds
12
Adenosine turnover
12
12
Number of compounds
12
SLC29 family
12
12
Number of compounds
12
C19: Ubiquitin-specific protease
11
11
Number of compounds
11
Endothelin receptors
11
11
Number of compounds
11
Formylpeptide receptors
11
11
Number of compounds
11
4A. Nerve growth factor IB-like receptors
11
11
Number of compounds
11
Acyltransferases
11
11
Number of compounds
11
ATPases
10
10
Number of compounds
10
RAS subfamily
10
10
Number of compounds
10
TIF1 family
10
10
Number of compounds
10
Neuropeptide Y receptors
10
10
Number of compounds
10
"CYP24, CYP26 and CYP27 families"
10
10
Number of compounds
10
Type VII RTKs: Neurotrophin receptor/Trk family
10
10
Number of compounds
10
CDK1 subfamily
9
9
Number of compounds
9
Organic anion transporters (OATs)
9
9
Number of compounds
9
Class I transporters
9
9
Number of compounds
9
Toll-like receptor family
9
9
Number of compounds
9
M1: Aminopeptidase N
9
9
Number of compounds
9
P2A P-type ATPases: Ca2+-ATPases
9
9
Number of compounds
9
Other PIKK family kinases
9
9
Number of compounds
9
T1: Proteasome
8
8
Number of compounds
8
Phosphatidylinositol 3-kinase family
8
8
Number of compounds
8
NAK family
8
8
Number of compounds
8
M2: Angiotensin-converting enzymes (ACE and ACE2)
8
8
Number of compounds
8
Kynurenine 3-monooxygenase
8
8
Number of compounds
8
SLC16 family of monocarboxylate transporters
8
8
Number of compounds
8
Type IV RTKs: VEGF (vascular endothelial growth factor) receptor family
8
8
Number of compounds
8
NADPH oxidases
8
8
Number of compounds
8
M12: Astacin/Adamalysin
8
8
Number of compounds
8
SLC43 family of large neutral amino acid transporters
8
8
Number of compounds
8
Proteinase-activated receptors
7
7
Number of compounds
7
CDK9 subfamily
7
7
Number of compounds
7
"GPR18, GPR55 and GPR119"
7
7
Number of compounds
7
Lysyl oxidases
7
7
Number of compounds
7
2B. Retinoid X receptors
7
7
Number of compounds
7
Somatostatin receptors
7
7
Number of compounds
7
AMPK subfamily
7
7
Number of compounds
7
Phospholipase A2
7
7
Number of compounds
7
GRK4 subfamily
7
7
Number of compounds
7
Iota subfamily
7
7
Number of compounds
7
Ribonucleoside-diphosphate reductases
7
7
Number of compounds
7
Beta-adrenergic receptor kinases (βARKs)
7
7
Number of compounds
7
"Type XI RTKs: TAM (TYRO3-, AXL- and MER-TK) receptor family"
7
7
Number of compounds
7
Calcium-sensing receptor
7
7
Number of compounds
7
Organic cation transporters (OCT)
7
7
Number of compounds
7
M14: Carboxypeptidase A
7
7
Number of compounds
7
SLC7 family
7
7
Number of compounds
7
VIP and PACAP receptors
6
6
Number of compounds
6
Vasopressin and oxytocin receptors
6
6
Number of compounds
6
Haem oxygenase
6
6
Number of compounds
6
Organic zwitterions/cation transporters (OCTN)
6
6
Number of compounds
6
Type II RTKs: Insulin receptor family
6
6
Number of compounds
6
Adenylyl cyclases (ACs)
6
6
Number of compounds
6
C14: Caspase
6
6
Number of compounds
6
Phosphatidylinositol kinases
6
6
Number of compounds
6
CLK family
6
6
Number of compounds
6
LIMK subfamily
6
6
Number of compounds
6
Amino acid hydroxylases
6
6
Number of compounds
6
GABA turnover
6
6
Number of compounds
6
Type X RTKs: HGF (hepatocyte growth factor) receptor family
6
6
Number of compounds
6
Cyclic GMP-AMP synthase
5
5
Number of compounds
5
CYP2 family: physiological enzymes subset
5
5
Number of compounds
5
SLC14 family of facilitative urea transporters
5
5
Number of compounds
5
eEF2K subfamily
5
5
Number of compounds
5
SLC47 family of multidrug and toxin extrusion transporters
5
5
Number of compounds
5
Methyltransferases
5
5
Number of compounds
5
P2Y receptors
5
5
Number of compounds
5
C54: Aut2 peptidase
5
5
Number of compounds
5
C2: Calpain
5
5
Number of compounds
5
Death-associated kinase (DAPK) family
5
5
Number of compounds
5
SLCO family of organic anion transporting polypeptides
5
5
Number of compounds
5
PAKB subfamily
5
5
Number of compounds
5
"CYP5, CYP7 and CYP8 families"
5
5
Number of compounds
5
FRAP subfamily
5
5
Number of compounds
5
CYP3 family
5
5
Number of compounds
5
CHK1 subfamily
5
5
Number of compounds
5
PDK1 family
5
5
Number of compounds
5
STE7 family
5
5
Number of compounds
5
CDK5 subfamily
5
5
Number of compounds
5
SLC35 family of nucleotide sugar transporters
5
5
Number of compounds
5
MAST family
5
5
Number of compounds
5
Urate transporter
4
4
Number of compounds
4
Sphingomyelin synthase
4
4
Number of compounds
4
Glutamate transporter subfamily
4
4
Number of compounds
4
Protein kinase A (PKA) family
4
4
Number of compounds
4
Type XIII RTKs: Ephrin receptor family
4
4
Number of compounds
4
SLC49 family of FLVCR-related heme transporters
4
4
Number of compounds
4
Thyroid hormone turnover
4
4
Number of compounds
4
p70 subfamily
4
4
Number of compounds
4
Cyclic nucleotide-regulated channels (CNG)
4
4
Number of compounds
4
3B. Estrogen-related receptors
4
4
Number of compounds
4
C13: Legumain
4
4
Number of compounds
4
Immunoglobulin like domain containing proteins
4
4
Number of compounds
4
Leukotriene receptors
4
4
Number of compounds
4
Hexose transporter family
4
4
Number of compounds
4
CAMK-unique family
4
4
Number of compounds
4
1A. Thyroid hormone receptors
4
4
Number of compounds
4
Orphan SLC38 transporters
4
4
Number of compounds
4
SRPK family
3
3
Number of compounds
3
SLC27 family of fatty acid transporters
3
3
Number of compounds
3
Type XII RTKs: TIE family of angiopoietin receptors
3
3
Number of compounds
3
SLC18 family of vesicular amine transporters
3
3
Number of compounds
3
Calcium activated chloride channel (CaCC)
3
3
Number of compounds
3
Delta subfamily
3
3
Number of compounds
3
Choline transporter
3
3
Number of compounds
3
Sphingomyelin phosphodiesterase
3
3
Number of compounds
3
Csk family
3
3
Number of compounds
3
Hydrogen sulphide synthesis
3
3
Number of compounds
3
N-Acylethanolamine turnover
3
3
Number of compounds
3
CD molecules
3
3
Number of compounds
3
Type XIV RTKs: RET
3
3
Number of compounds
3
Fatty acid-binding proteins
3
3
Number of compounds
3
TAO subfamily
3
3
Number of compounds
3
Aquaporins
3
3
Number of compounds
3
KHS subfamily
3
3
Number of compounds
3
Melanocortin receptors
3
3
Number of compounds
3
Decarboxylases
3
3
Number of compounds
3
Tau tubulin kinase (TTBK) family
3
3
Number of compounds
3
Carboxylases
3
3
Number of compounds
3
SLC52 family of riboflavin transporters
3
3
Number of compounds
3
Serine palmitoyltransferase
3
3
Number of compounds
3
Sugar phosphatases
3
3
Number of compounds
3
S8: Subtilisin
3
3
Number of compounds
3
Cholecystokinin receptors
3
3
Number of compounds
3
CAMK2 family
3
3
Number of compounds
3
Chloride/bicarbonate exchangers
3
3
Number of compounds
3
SLC15 family of peptide transporters
3
3
Number of compounds
3
MAPKAPK subfamily
3
3
Number of compounds
3
STE11 family
3
3
Number of compounds
3
Type XVII RTKs: ROS receptors
3
3
Number of compounds
3
Type I receptor serine/threonine kinases
3
3
Number of compounds
3
Eta subfamily
3
3
Number of compounds
3
Isocitrate dehydrogenases
3
3
Number of compounds
3
S10: Carboxypeptidase Y
3
3
Number of compounds
3
Orexin receptors
3
3
Number of compounds
3
Peptidyl-prolyl cis/trans isomerases
3
3
Number of compounds
3
Melanin-concentrating hormone receptors
2
2
Number of compounds
2
WEE family
2
2
Number of compounds
2
SLC34 family of sodium phosphate co-transporters
2
2
Number of compounds
2
M16: Pitrilysin
2
2
Number of compounds
2
Relaxin family peptide receptors
2
2
Number of compounds
2
CDK8 subfamily
2
2
Number of compounds
2
MST subfamily
2
2
Number of compounds
2
SLC13 family of sodium-dependent sulphate/carboxylate transporters
2
2
Number of compounds
2
Purine-nucleoside phosphorylase
2
2
Number of compounds
2
Fer family
2
2
Number of compounds
2
MSK subfamily
2
2
Number of compounds
2
Exchange protein activated by cyclic AMP (EPACs)
2
2
Number of compounds
2
TKL-unique family
2
2
Number of compounds
2
Acid-sensing (proton-gated) ion channels (ASICs)
2
2
Number of compounds
2
Acid ceramidase
2
2
Number of compounds
2
Sialic acid transporter
2
2
Number of compounds
2
2E. Tailless-like receptors
2
2
Number of compounds
2
Ghrelin receptor
2
2
Number of compounds
2
Type II receptor serine/threonine kinases
2
2
Number of compounds
2
Integrins
2
2
Number of compounds
2
UDP glucuronosyltransferases (UGT)
2
2
Number of compounds
2
Platelet-activating factor receptor
2
2
Number of compounds
2
SLC12 family of cation-coupled chloride transporters
2
2
Number of compounds
2
SLC42 family of Rhesus glycoprotein ammonium transporters
2
2
Number of compounds
2
Class C Orphans
2
2
Number of compounds
2
Corticotropin-releasing factor receptors
2
2
Number of compounds
2
C12: Ubiquitin C-terminal hydrolase
2
2
Number of compounds
2
Other PEK family kinases
2
2
Number of compounds
2
B-cell lymphoma 2 (Bcl-2) protein family
2
2
Number of compounds
2
SGK family
2
2
Number of compounds
2
Lysophospholipid (LPA) receptors
2
2
Number of compounds
2
Heat shock proteins
2
2
Number of compounds
2
Tumour necrosis factor (TNF) receptor family
2
2
Number of compounds
2
Connexins and Pannexins
2
2
Number of compounds
2
Succinate receptor
2
2
Number of compounds
2
Neutral sphingomyelinase coupling factors
2
2
Number of compounds
2
CRK7 subfamily
2
2
Number of compounds
2
Neuropeptide FF/neuropeptide AF receptors
1
1
Number of compounds
1
Myosin Light Chain Kinase (MLCK) family
1
1
Number of compounds
1
Opsin receptors
1
1
Number of compounds
1
TAF1 family
1
1
Number of compounds
1
RCK family
1
1
Number of compounds
1
RIO2 subfamily
1
1
Number of compounds
1
NIMA (never in mitosis gene a)- related kinase (NEK) family
1
1
Number of compounds
1
Chitinases
1
1
Number of compounds
1
Membrane bound O-acyltransferases
1
1
Number of compounds
1
CYP4 family
1
1
Number of compounds
1
Neurotensin receptors
1
1
Number of compounds
1
"Inositol 1,4,5-trisphosphate 3-kinases"
1
1
Number of compounds
1
CCRK subfamily
1
1
Number of compounds
1
RSK subfamily
1
1
Number of compounds
1
Phosphoinositide-specific phospholipase C
1
1
Number of compounds
1
Galanin receptors
1
1
Number of compounds
1
STE20 subfamily
1
1
Number of compounds
1
Methyllysine reader proteins
1
1
Number of compounds
1
Sphingolipid Δ4-desaturase
1
1
Number of compounds
1
1-phosphatidylinositol 4-kinase family
1
1
Number of compounds
1
Prokineticin receptors
1
1
Number of compounds
1
M18: Aminopeptidase I
1
1
Number of compounds
1
ILK subfamily
1
1
Number of compounds
1
Protein kinase N (PKN) family
1
1
Number of compounds
1
Nuclear export proteins
1
1
Number of compounds
1
SLC10 family of sodium-bile acid co-transporters
1
1
Number of compounds
1
Inositol polyphosphate phosphatases
1
1
Number of compounds
1
Aryl hydrocarbon receptor
1
1
Number of compounds
1
SLC54 Mitochondrial pyruvate carriers
1
1
Number of compounds
1
STE-unique family
1
1
Number of compounds
1
Adiponectin receptors
1
1
Number of compounds
1
MELK subfamily
1
1
Number of compounds
1
PRP4 subfamily
1
1
Number of compounds
1
Kelch-like proteins
1
1
Number of compounds
1
SLC9 family of sodium/hydrogen exchangers
1
1
Number of compounds
1
Ceramide glucosyltransferase
1
1
Number of compounds
1
HIPK subfamily
1
1
Number of compounds
1
Syk family
1
1
Number of compounds
1
Arginase
1
1
Number of compounds
1
ATR subfamily
1
1
Number of compounds
1
NuaK subfamily
1
1
Number of compounds
1
Phosphatidylinositol phosphate kinases
1
1
Number of compounds
1
Inositol monophosphatase
1
1
Number of compounds
1
Unc-51-like kinase (ULK) family
1
1
Number of compounds
1
SLC45 family of putative sugar transporters
1
1
Number of compounds
1
MARK subfamily
1
1
Number of compounds
1
"Akt (Protein kinase B, PKB) family"
1
1
Number of compounds
1
5A. Fushi tarazu F1-like receptors
1
1
Number of compounds
1
Glucagon receptor family
1
1
Number of compounds
1
Meta subfamily
1
1
Number of compounds
1
Ack family
1
1
Number of compounds
1
Inhibitors of apoptosis (IAP) protein family
1
1
Number of compounds
1
BRSK subfamily
1
1
Number of compounds
1
SLC28 family
1
1
Number of compounds
1
Apelin receptor
1
1
Number of compounds
1
SLC65 NPC-type cholesterol transporters
1
1
Number of compounds
1
TESK subfamily
1
1
Number of compounds
1
Motilin receptor
1
1
Number of compounds
1
Sphingosine kinase
1
1
Number of compounds
1
SLC46 family of folate transporters
1
1
Number of compounds
1
Mitochondrial phosphate transporters
1
1
Number of compounds
1
CDK7 subfamily
1
1
Number of compounds
1
Type XIX RTKs: Leukocyte tyrosine kinase (LTK) receptor family
1
1
Number of compounds
1
EBCL-0045