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Chemical probes are specific small molecules used in biological research to investigate the function and behavior of biomolecules within cells or organisms. These probes are designed to interact with their target molecules in a highly selective and often reversible manner, enabling researchers to modulate the activity of the target and study its biological effects. It is a gateway to understanding fundamental biological processes, aiding in developing first-in-class drugs.
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CAS#:
53123-88-9
Name:
Target:
Serine/threonine-protein kinase mTOR | pX = 9.7
Target action:
Inhibitor
doi
Properties:
MW:
913.555
|
cLogP:
7.039
$51/5 mg
(EBC)
1
CAS#:
2305480-97-9
Name:
Target:
melatonin receptor type 1a | pX = 8.12
Target action:
Radioligand (/ligand)
doi
Properties:
MW:
363.64
|
cLogP:
4.017
$120/5 mg
(EBC)
1
CAS#:
2055397-28-7
Name:
Target:
Histone acetyltransferase KAT6A | pX = 8.2
Target action:
Inhibitor
doi
Properties:
MW:
389.376
|
cLogP:
2.468
$104/5 mg
(EBC)
1
CAS#:
1234480-46-6
Name:
Target:
Activated CDC42 kinase 1 | pX = 8.7
Target action:
Radioligand (/ligand)
doi
Properties:
MW:
445.223
|
cLogP:
4.892
$138/5 mg
(EBC)
1
CAS#:
2166387-65-9
Name:
Target:
B-cell lymphoma 6 protein | pX = 8.52
Target action:
Inhibitor
doi
Properties:
MW:
484.199
|
cLogP:
3.817
$230/5 mg
(EBC)
1
CAS#:
1032900-25-6
Name:
Target:
ALK tyrosine kinase receptor | pX = 9.7
Target action:
Inhibitor
doi
Properties:
MW:
557.223
|
cLogP:
6.713
$19/5 mg
(EBC)
1
CAS#:
1801344-14-8
Name:
Target:
Interleukin-1 receptor-associated kinase 4 | pX = 7.5
Target action:
Inhibitor
doi
Properties:
MW:
491.499
|
cLogP:
1.056
$80/5 mg
(EBC)
1
CAS#:
1403254-99-8
Name:
Target:
Histone-lysine N-methyltransferase EZH2 | pX = 8.6
Target action:
Inhibitor
doi
Properties:
MW:
572.336
|
cLogP:
3.378
$67/5 mg
(EBC)
1
CAS#:
1332331-08-4
Name:
Target:
fatty acid synthase | pX = 8.1
Target action:
Inhibitor
doi
Properties:
MW:
428.185
|
cLogP:
3.546
$120/5 mg
(EBC)
1
CAS#:
1206161-97-8
Name:
Target:
Tyrosine-protein kinase JAK1 | pX = 8
Target action:
Inhibitor
doi
Properties:
MW:
425.504
|
cLogP:
1.831
$19/5 mg
(EBC)
1
CAS#:
212481-66-8
Name:
Target:
Endothelin-1 receptor | pX = 9.34
Target action:
Radioligand (/ligand)
doi
Properties:
MW:
532.712
|
cLogP:
5.609
$396/5 mg
(EBC)
1
CAS#:
1028486-01-2
Name:
Target:
Aurora kinase A | pX = 8.46
doi
Properties:
MW:
518.924
|
cLogP:
4.73
$55/5 mg
(EBC)
1
CAS#:
115199-84-3
Name:
Target:
Kappa-type opioid receptor | pX = 10.4
doi
Properties:
MW:
391.334
|
cLogP:
5.034
$113/5 mg
(EBC)
1
CAS#:
1693731-40-6
Name:
Target:
Pirin | pX = 7.36
Target action:
Radioligand (/ligand)
doi
Properties:
MW:
552.62
|
cLogP:
5.169
$195/5 mg
(EBC)
1
CAS#:
2411085-89-5
Name:
Target:
GSPT1 | pX = 7.17
Target action:
Radioligand (/ligand)
doi
Properties:
MW:
774.707
|
cLogP:
6.322
$1865/5 mg
(EBC)
1
CAS#:
1346623-17-3
Name:
Target:
C5a anaphylatoxin chemotactic receptor 1 | pX = 7.34
Target action:
Inhibitor
doi
Properties:
MW:
581.267
|
cLogP:
8.191
$71/5 mg
(EBC)
1
CAS#:
1196109-52-0
Name:
Target:
fatty acid amide hydrolase | pX = 9.22
Target action:
Inhibitor
doi
Properties:
MW:
456.177
|
cLogP:
4.893
$53/5 mg
(EBC)
1
CAS#:
2097381-85-4
Name:
Target:
von Hippel-Lindau disease tumor suppressor | pX = 7.05
Target action:
Radioligand (/ligand)
doi
Properties:
MW:
523.225
|
cLogP:
1.945
$111/5 mg
(EBC)
1
CAS#:
649735-46-6
Name:
Target:
Vascular endothelial growth factor receptor 2 | pX = 7.59
doi
Properties:
MW:
370.378
|
cLogP:
3.346
$150/5 mg
(EBC)
1
CAS#:
2757254-99-0
Name:
Target:
Protein O-GlcNAcase | pX = 7.34
Target action:
Inhibitor
doi
Properties:
MW:
286.375
|
cLogP:
1.89
$257/5 mg
(EBC)
1
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