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Product details:
ID
CAS
2326521-71-3
Purity
95%
MRTX849 is a covalent inhibitor of K-RasG12C (IC50 = 0.19 nM) , a mutant form of K-Ras that accumulates in cancer cells. Indicated for the treatment of locally advanced or metastatic KRAS G12C-mutated non-small cell lung cancer in patients who have received at least one prior systemic therapy.
Properties
Name
MRTX849
Smiles
CN1CCC[C@H]1COC=2N=C(N3CCN([C@@H](CC#N)C3)C(=O)C(=C)F)C=4CCN(CC4N2)C=5C=CC=C6C=CC=C(Cl)C56
Targets
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Target name
Target pX
Target action
doi
SDS
MRTX849 | adagrasib
No data available
The compound has purity validated by NMR and/or LCMS methods.
1 mg
$37
2 mg
$39
5 mg
$41
10 mg
$43
15 mg
$45
20 mg
$48
25 mg
$53
30 mg
$56
35 mg
$59
40 mg
$61
45 mg
$64
50 mg
$66
75 mg
$69
100 mg
$POA
Quantity
1
Total amount
$ 41
MRTX849 | adagrasib
No data available
The compound has purity validated by NMR and/or LCMS methods.
Target activity features
It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.