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Product details:
CAS
1480833-70-2
Purity
95%
PF-04885614 is a potent NaV1.8 inhibitor. PF-04885614 has potential for neurological and neurodevelopmental diseases treatment.
Properties
Name
PF-04885614
Smiles
CC(C)(N)C1=NC(=CN1)C=2C=CC(OC(F)(F)F)=CC2
Targets
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Sold for research purposes under agreement from Pfizer Inc.
PF-04885614, also referred to as PF 04885614 and PF-04885614, is a research compound used in studies of metabolic regulation and nuclear receptor signaling. Identified under CAS 1480833-70-2, this molecule is associated with selective modulation of pathways linked to energy balance, glucose metabolism, and transcriptional regulation. PF-04885614 Pfizer programs have contributed to its recognition as a useful reference compound in metabolic and endocrine research.
Researchers commonly evaluate PF-04885614 chemical structure to understand how the molecule interacts with specific receptor targets and co-regulatory proteins. In addition, PF-04885614 molecular weight is considered during assay preparation and dosing calculations, ensuring consistent experimental conditions across different study formats.
Application PF-04885614 is primarily focused on studies involving nuclear receptor activity and metabolic pathway modulation. It is used in research exploring transcriptional control mechanisms and their impact on cellular energy homeostasis.
Its defined activity profile supports its use in both early-stage discovery and mechanistic studies where pathway selectivity is essential.
The biochemical action of PF-04885614 involves selective interaction with nuclear receptor complexes, influencing gene expression patterns associated with metabolism and energy regulation. This activity allows researchers to explore how specific pathways contribute to cellular responses under different physiological conditions.
From a physiological perspective, PF-04885614 is relevant in studies of glucose utilization, lipid metabolism, and hormone-regulated processes. Its ability to modulate transcriptional activity makes it valuable for investigating disease mechanisms linked to metabolic imbalance.
PF-04885614 offers a combination of selectivity and experimental reliability, making it suitable for a range of research applications. When sourced as EBC-498091, it is supported by quality control and analytical validation, ensuring consistency in laboratory use.
As part of a broader collection of bioactive compounds, PF-04885614 enables researchers to investigate complex regulatory mechanisms and refine experimental workflows with confidence. Its integration into screening and validation studies supports a deeper understanding of metabolic signaling networks.
SDS
No records
No data available
The compound has purity validated by NMR and/or LCMS methods.
1 mg
$46
2 mg
$48
5 mg
$49
10 mg
$50
15 mg
$51
20 mg
$52
25 mg
$57
30 mg
$61
35 mg
$69
40 mg
$76
45 mg
$83
50 mg
$90
75 mg
$96
100 mg
$POA
Quantity
1
Total amount
$ 49
No records
No data available
The compound has purity validated by NMR and/or LCMS methods.
Target activity features
It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.
CAS:1480833-70-2
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