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Product details:
CAS
1539296-45-1
Purity
95%
PF470 is a potent negative allosteric modulator of the Metabotropic Glutamate Receptor 5 (GRM5). It binds to GRM5 with a Ki of 0.9 nM. PF470 reduces dyskinesia in a rodent (MPTP)-rendered Parkinsonian model of L-DOPA-induced dyskinesia (PD-LID).
Properties
Name
PF470
Smiles
CC=1C=CN=CC1C2=NN(C)C=3N=C(OCC=4C=CC=CN4)C=NC23
Targets
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Sold for research purposes under agreement from Pfizer Inc.
Target name
Target pX
Target action
doi
SDS
No records
No data available
The compound has purity validated by NMR and/or LCMS methods.
1 mg
$75
2 mg
$79
5 mg
$84
10 mg
$110
15 mg
$136
20 mg
$162
25 mg
$176
30 mg
$194
35 mg
$212
40 mg
$231
45 mg
$246
50 mg
$268
75 mg
$POA
100 mg
$POA
Quantity
1
Total amount
$ 84
No records
No data available
The compound has purity validated by NMR and/or LCMS methods.
Target activity features
It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.