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Product details:
CAS
334949-59-6
Purity
95%
BIX-02188 potent, selective MEK5 inhibitor (IC50 = 4.3 nM). Blocks phosphorlyation of ERK5, without affecting phosphorylation of ERK1/2. Induces apoptosis in FLT3-ITD cells. Centrally active in vivo.
Properties
Name
BIX-02188
Smiles
CN(C)CC=1C=CC=C(NC(=C2C(=O)NC=3C=C(C=CC23)C(=O)N)C=4C=CC=CC4)C1
Targets
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Target name
Target pX
Target action
doi
BIX 02188
No data available
The compound has purity validated by NMR and/or LCMS methods.
1 mg
$85
2 mg
$89
5 mg
$177
10 mg
$307
15 mg
$371
20 mg
$436
25 mg
$530
30 mg
$624
35 mg
$719
40 mg
$813
45 mg
$872
50 mg
$930
75 mg
$1237
100 mg
Get a quoteQuantity
1
Total amount
$ 177
BIX 02188
No data available
The compound has purity validated by NMR and/or LCMS methods.
Target activity features
It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.