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Product details:

BIX-02188

Search by this structure
Molecule product

ID

EBC-420068

CAS

334949-59-6

Purity

95%

BIX-02188 potent, selective MEK5 inhibitor (IC50 = 4.3 nM). Blocks phosphorlyation of ERK5, without affecting phosphorylation of ERK1/2. Induces apoptosis in FLT3-ITD cells. Centrally active in vivo.

Properties

cLogP:2.859
MW:412.19

Name

BIX-02188

Smiles

CN(C)CC=1C=CC=C(NC(=C2C(=O)NC=3C=C(C=CC23)C(=O)N)C=4C=CC=CC4)C1

Targets

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Chemical probes

Target name

Target pX

Target action

doi

MAP2K5

8.37

Open link
Synonyms

BIX 02188

Transportation & Handlings
Storage temperature:RT
Transport temperature:Standard
Dangerous goods:No
Solubility

No data available

Purity & Quality Control

The compound has purity validated by NMR and/or LCMS methods.

Prices

1 mg

$85

2 mg

$89

5 mg

$177

10 mg

$307

15 mg

$371

20 mg

$436

25 mg

$530

30 mg

$624

35 mg

$719

40 mg

$813

45 mg

$872

50 mg

$930

75 mg

$1237

100 mg

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Quantity

-

1

+

Total amount

$ 177

Your current project

In Stock

Synonyms

BIX 02188

Transportation & Handlings
Storage temperature:RT
Transport temperature:Standard
Dangerous goods:No
Solubility

No data available

Purity & Quality Control

The compound has purity validated by NMR and/or LCMS methods.

Target activity features

It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.

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Related Compounds

EBC-420068
EBC-420068

CAS:334949-59-6

BIX-02188
BIX-02188
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