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Product details:
CAS
2064292-12-0
Purity
95%
A1874 is a nutlin-based and BRD4-degrading PROTAC with a EC50 of 32 nM. Effective in inhibiting many cancer cell lines proliferation.
Properties
Name
A1874
Smiles
COC=1C=C(C=CC1NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@@](C#N)([C@H]2C=3C=CC=C(Cl)C3F)C=4C=CC(Cl)=CC4F)C(=O)NCCOCCOCCOCCNC(=O)C[C@@H]5N=C(C=6C(C)=C(C)SC6N7C(C)=NN=C57)C=8C=CC(Cl)=CC8
Targets
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Target name
Target pX
Target action
doi
A1874
No data available
The compound has purity validated by NMR and/or LCMS methods.
1 mg
$85
2 mg
$89
5 mg
$177
10 mg
$307
15 mg
$371
20 mg
$436
25 mg
$530
30 mg
$624
35 mg
$719
40 mg
$813
45 mg
$872
50 mg
$930
75 mg
$1237
100 mg
$POA
Quantity
1
Total amount
$ 177
A1874
No data available
The compound has purity validated by NMR and/or LCMS methods.
Target activity features
It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.