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Product details:

MD-224

Molecule product

ID

EBC-413042

CAS

2136247-12-4

Purity

95%

MD-224 is a highly potent small-molecule murine double minute 2 (MDM2) degrader based on the proteolysistargeting chimera (PROTAC) concept.

Properties

cLogP:6.432
MW:888.261

Name

MD-224

Smiles

FC=1C(Cl)=CC=CC1[C@H]2[C@@H](NC3(CCCCC3)[C@@]24C(=O)NC=5C=C(Cl)C=CC54)C(=O)NC=6C=CC(=CC6)C(=O)NCCCC#CC=7C=CC=C8C(=O)N(CC87)C9CCC(=O)NC9=O

Targets

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Chemical probes

Target name

Target pX

Target action

doi

E3 ubiquitin-protein ligase Mdm2

8.82

Inhibitor

Open link
Product datasheets

SDS

Synonyms

MD-224

Transportation & Handlings
Storage temperature:RT
Transport temperature:Standard
Dangerous goods:No
Solubility

No data available

Purity & Quality Control

The compound has purity validated by NMR and/or LCMS methods.

Molarity Calculator
Dilution Calculator
Formulation Calculator

Prices

Temporarily unavailable

1 mg

$85

2 mg

$87

5 mg

$174

10 mg

$301

15 mg

$364

20 mg

$428

25 mg

$520

30 mg

$613

35 mg

$705

40 mg

$798

45 mg

$856

50 mg

$913

75 mg

$1214

100 mg

$POA

Quantity

-

1

+

Total amount

$ 174

Your current project

Temporarily unavailable

Synonyms

MD-224

Transportation & Handlings
Storage temperature:RT
Transport temperature:Standard
Dangerous goods:No
Solubility

No data available

Purity & Quality Control

The compound has purity validated by NMR and/or LCMS methods.

Target activity features

It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.