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Product details:
ID
CAS
1380288-87-8
Purity
95%
EPZ-5676 is a potent and selective small-molecule DOT1L inhibitor (Ki = 80 pM) with sub-nanomolar affinity for DOT1L and > 37,000-fold selectivity against other histone methyltransferases.
Properties
Name
EPZ-5676
Smiles
CC(C)N(C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=NC=3C(N)=NC=NC23)[C@H]4C[C@@H](CCC5=NC=6C=CC(=CC6N5)C(C)(C)C)C4
Targets
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Target name
Target pX
Target action
doi
SDS
EPZ-5676 | pinometostat
No data available
The compound has purity validated by NMR and/or LCMS methods.
1 mg
$90
2 mg
$94
5 mg
$98
10 mg
$117
15 mg
$158
20 mg
$199
25 mg
$237
30 mg
$276
35 mg
$306
40 mg
$337
45 mg
$363
50 mg
$400
75 mg
$553
100 mg
$POA
Quantity
1
Total amount
$ 98
EPZ-5676 | pinometostat
No data available
The compound has purity validated by NMR and/or LCMS methods.
Target activity features
It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.
CAS: 1380288-87-8
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