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Product details:
CAS
104987-11-3
Purity
95%
Tacrolimus is a calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis. Tacrolimus inhibits T-lymphocyte activation by first binding to an intracellular protein, FKBP-12. A complex of tacrolimus-FKBP-12, calcium, calmodulin, and calcineurin is then formed and the phosphatase activity of calcineurin is inhibited.
Properties
Name
Tacrolimus
Smiles
CO[C@@H]1C[C@@H](CC[C@H]1O)/C=C(\C)/[C@H]2OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@]4(O)O[C@@H]([C@H](C[C@H]4C)OC)[C@H](C[C@@H](C)C\C(=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]2C)\C)OC
Targets
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SDS
FK-506 | FK506 | TAC | Tacrolimus
No data available
The compound has purity validated by NMR and/or LCMS methods.
1 mg
$121
2 mg
$127
5 mg
$138
10 mg
$153
15 mg
$216
20 mg
$278
25 mg
$345
30 mg
$389
35 mg
$433
40 mg
$472
45 mg
$520
50 mg
$558
75 mg
$816
100 mg
$928
Quantity
1
Total amount
$ 138
FK-506 | FK506 | TAC | Tacrolimus
No data available
The compound has purity validated by NMR and/or LCMS methods.
Target activity features
It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.
CAS:104987-11-3
0
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