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Product details:
CAS
109581-93-3
Purity
95%
Tacrolimus is a calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis. Tacrolimus inhibits T-lymphocyte activation by first binding to an intracellular protein, FKBP-12. A complex of tacrolimus-FKBP-12, calcium, calmodulin, and calcineurin is then formed and the phosphatase activity of calcineurin is inhibited.
Properties
Name
Tacrolimus hydrate
Smiles
O.CO[C@@H]1C[C@@H](CC[C@H]1O)C=C(C)[C@H]2OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@]4(O)O[C@@H]([C@H](C[C@H]4C)OC)[C@H](C[C@@H](C)CC(=C[C@@H](CC=C)C(=O)C[C@H](O)[C@H]2C)C)OC
Targets
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SDS
FK506 | Tacrolimus
No data available
The compound has purity validated by NMR and/or LCMS methods.
1 mg
$47
2 mg
$49
5 mg
$50
10 mg
$51
15 mg
$52
20 mg
$53
25 mg
$59
30 mg
$65
35 mg
$73
40 mg
$80
45 mg
$87
50 mg
$94
75 mg
$100
100 mg
$102
Quantity
1
Total amount
$ 50
FK506 | Tacrolimus
No data available
The compound has purity validated by NMR and/or LCMS methods.
Target activity features
It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.
CAS:104987-11-3
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CAS:104987-11-3
0