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Product details:

Irinotecan

Search by this structure
Molecule product

ID

EBC-17160

CAS

97682-44-5

Purity

95%

Irinotecan is an antineoplastic enzyme inhibitor primarily used in the treatment of colorectal cancer. It is a derivative of camptothecin that inhibits the action of topoisomerase I. Irinotecan prevents religation of the DNA strand by binding to topoisomerase I-DNA complex, and causes double-strand DNA breakage and cell death.

Properties

cLogP:2.728
MW:586.279
Pharmacopoeia:FDA

Name

Irinotecan

Smiles

CCC=1C=2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2N=C5C=CC(OC(=O)N6CCC(CC6)N7CCCCC7)=CC15

Targets

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Synonyms

CPT-11 | IRN | Iri | MM-398 | SN38 | camptosar | camptothecin-11 | irinotecan | irinotecan hydrochloride

Transportation & Handlings
Storage temperature:RT
Transport temperature:Standard
Dangerous goods:No
Solubility

No data available

Purity & Quality Control

The compound has purity validated by NMR and/or LCMS methods.

Prices

Temporarily unavailable

1 mg

$19

2 mg

$28

5 mg

$56

10 mg

$97

15 mg

$118

20 mg

$139

25 mg

$169

30 mg

$199

35 mg

$229

40 mg

$72

45 mg

$277

50 mg

$296

75 mg

$393

100 mg

$94

Quantity

-

1

+

Total amount

$ 56

Your current project

Temporarily unavailable

Synonyms

CPT-11 | IRN | Iri | MM-398 | SN38 | camptosar | camptothecin-11 | irinotecan | irinotecan hydrochloride

Transportation & Handlings
Storage temperature:RT
Transport temperature:Standard
Dangerous goods:No
Solubility

No data available

Purity & Quality Control

The compound has purity validated by NMR and/or LCMS methods.

Target activity features

It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.

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Related Compounds

EBC-12141
EBC-12141

CAS:100286-90-6

Irinotecan hydrochloirde
Irinotecan hydrochlo...
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