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Product details:
CAS
835616-60-9
Purity
95%
Thalidomide 4-fluoride is a precursor in the synthesis of PROTACs. It can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1. Thalidomide 4-fluoride is a cereblon ligand, Kd = 0.35 μM.
Properties
Name
Thalidomide 4-fluoride
Smiles
FC=1C=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C21
Targets
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SDS
2-(2,6-dioxo-3-piperidyl)-4-fluoroisoindoline-1,3-dione | 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindolin-1,3-dione | 4-fluorothalidomide | Cereblon ligand 4 | E3 ligase Ligand 4 | TC-E3 5032 | thalidomide 4-fluoride | thalidomide fluoride
No data available
The compound has purity validated by NMR and/or LCMS methods.
1 mg
$19
2 mg
$19
5 mg
$19
10 mg
$19
15 mg
$19
20 mg
$19
25 mg
$19
30 mg
$19
35 mg
$19
40 mg
$19
45 mg
$19
50 mg
$19
75 mg
$19
100 mg
$POA
Quantity
1
Total amount
$ 19
2-(2,6-dioxo-3-piperidyl)-4-fluoroisoindoline-1,3-dione | 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindolin-1,3-dione | 4-fluorothalidomide | Cereblon ligand 4 | E3 ligase Ligand 4 | TC-E3 5032 | thalidomide 4-fluoride | thalidomide fluoride
No data available
The compound has purity validated by NMR and/or LCMS methods.
Target activity features
It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.