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Product details:
CAS
1275595-86-2
Purity
95%
Selatinib is a a potent dual EGFR/HER-2 inhibitor. Selatinib is also an analog of the quinazoline lapatinib with potential antineoplastic activity. Upon administration, selatinib reversibly blocks phosphorylation of both EGFR and ErbB2, thereby suppressing tumor growth in EGFR/ErbB-2-overexpressing tumor cells. The tyrosine kinases EGFR and ErbB2 have been implicated in the growth of various tumor types.
Properties
Name
Selatinib
Smiles
CS(=O)CCNCC1=CC=C(O1)C=2C=CC=3N=CN=C(NC=4C=CC(OCC=5C=CC=C(F)C5)=C(Cl)C4)C3C2
Targets
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selatinib
No data available
The compound has purity validated by NMR and/or LCMS methods.
1 mg
$174
2 mg
$260
5 mg
$520
10 mg
$900
15 mg
$1097
20 mg
$1177
25 mg
$1454
30 mg
$1731
35 mg
$2008
40 mg
$2285
45 mg
$2562
50 mg
$2839
75 mg
$4154
100 mg
$POA
Quantity
1
Total amount
$ 520
selatinib
No data available
The compound has purity validated by NMR and/or LCMS methods.
Target activity features
It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.