Compound libraries
Products
EBC main page
Search
Dyes
Impurities
Chemical probes
Contacts us
Pfizer reference compounds
Services
Back
Product details:
CAS
2262452-06-0
Purity
95%
RU.521 is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor and inhibits cGAS-mediated interferon upregulation. Also it reduces constitutive expression of interferon in macrophages from a mouse model of Aicardi-Goutières syndrome (AGS).
Properties
Name
RU.521
Smiles
CC1=NN(C(O)=C1C2OC(=O)C=3C=CC=CC23)C4=NC=5C=CC(Cl)=C(Cl)C5N4
Targets
Please log in to see this information
Target name
Target pX
Target action
doi
RU320521
No data available
The compound has purity validated by NMR and/or LCMS methods.
1 mg
$94
2 mg
$98
5 mg
$102
10 mg
$122
15 mg
$165
20 mg
$208
25 mg
$247
30 mg
$288
35 mg
$319
40 mg
$351
45 mg
$378
50 mg
$417
75 mg
$576
100 mg
$POA
Quantity
1
Total amount
$ 102
RU320521
No data available
The compound has purity validated by NMR and/or LCMS methods.
Target activity features
It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.