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Product details:
CAS
1334546-77-8
Purity
95%
Icenticaftor is a potentiator of CFTR for both in vitro and in vivo work. It is selective for the potentiation of CFTR against a broad panel of 46 G-protein coupled receptor, enzyme, transporter, and ion channels (including hERG) as well as 20 kinase targets with no observed inhibition >50% at 10 μM concentration.
Properties
Name
Icenticaftor
Smiles
COC=1N=C(C(=O)NC[C@](C)(O)C(F)(F)F)C(N)=CC1C(F)(F)F
Targets
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Target name
Target pX
Target action
doi
QBW251
No data available
The compound has purity validated by NMR and/or LCMS methods.
1 mg
$156
2 mg
$234
5 mg
$467
10 mg
$809
15 mg
$980
20 mg
$1152
25 mg
$1400
30 mg
$1649
35 mg
$1898
40 mg
$2147
45 mg
$2303
50 mg
$2458
75 mg
$3267
100 mg
$POA
Quantity
1
Total amount
$ 467
QBW251
No data available
The compound has purity validated by NMR and/or LCMS methods.
Target activity features
It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.