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Product details:
CAS
1360821-21-1
Purity
95%
RO2468 is an excellent chemical probe and although the selectivity data is lacking, the biological effect in p53 WT vs MUT cell lines looks convincing (over 700 fold difference in IC50s).
Properties
Name
RO2468
Smiles
COC=1C=C(C=CC1NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@]3([C@H]2C=4C=CC=C(Cl)C4F)C(=O)NC=5C=C(Cl)N=CC53)C(=O)N
Targets
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Target name
Target pX
Target action
doi
RO2468
No data available
The compound has purity validated by NMR and/or LCMS methods.
1 mg
$POA
2 mg
$POA
5 mg
$POA
10 mg
$POA
15 mg
$POA
20 mg
$POA
25 mg
$POA
30 mg
$POA
35 mg
$POA
40 mg
$POA
45 mg
$POA
50 mg
$POA
75 mg
$POA
100 mg
$POA
Quantity
1
Total amount
$ 0
RO2468
No data available
The compound has purity validated by NMR and/or LCMS methods.
Target activity features
It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.