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Product details:
CAS
1360821-61-9
Purity
95%
RO5353 is an excellent probe to study the in vitro and in vivo biology of p53-MDM2 inhibition. It is potent, has excellent cellular selectivity and robust in-vivo efficacy.
Properties
Name
RO5353
Smiles
COC=1C=C(C=CC1NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@]3([C@H]2C=4C=CC=C(Cl)C4F)C(=O)NC=5C=C(Cl)SC53)C(=O)N
Targets
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Target name
Target pX
Target action
doi
SDS
RO5353
No data available
The compound has purity validated by NMR and/or LCMS methods.
1 mg
$POA
2 mg
$POA
5 mg
$POA
10 mg
$POA
15 mg
$POA
20 mg
$POA
25 mg
$POA
30 mg
$POA
35 mg
$POA
40 mg
$POA
45 mg
$POA
50 mg
$POA
75 mg
$POA
100 mg
$POA
Quantity
1
Total amount
$ 0
RO5353
No data available
The compound has purity validated by NMR and/or LCMS methods.
Target activity features
It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.