Chlorthalidone impurity A (EBC-75128)
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Product details:
CAS
77-36-1
Purity
95%
Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through inhibition of the Na+/Cl− symporter in the distal convoluted tubule cells in the kidney. The exact mechanism of chlorthalidone's anti-hypertensive effect is under debate, however, it is thought that increased diuresis results in decreased plasma and extracellular fluid volume, decreased cardiac output and therefore overall reduction in blood pressure.
Properties
Name
Chlorthalidone
Smiles
NS(=O)(=O)C=1C=C(C=CC1Cl)C2(O)NC(=O)C=3C=CC=CC32
Targets
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SDS
chlorthalidon | chlorthalidone
No data available
The compound has purity validated by NMR and/or LCMS methods.
1 mg
$61
2 mg
$66
5 mg
$71
10 mg
$90
15 mg
$99
20 mg
$107
25 mg
$120
30 mg
$129
35 mg
$138
40 mg
$155
45 mg
$166
50 mg
$180
75 mg
$255
100 mg
$300
Quantity
1
Total amount
$ 71
chlorthalidon | chlorthalidone
No data available
The compound has purity validated by NMR and/or LCMS methods.
Target activity features
It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.