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Product details:
CAS
2628280-40-8
Purity
95%
Nirmatrelvir is a potent and orally active SARS-CoV 3C-like protease inhibitor (IC50 = 0.79 nM).
Properties
Name
Nirmatrelvir
Smiles
CC(C)(C)[C@H](NC(=O)C(F)(F)F)C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)N[C@@H](C[C@@H]3CCNC3=O)C#N)C2(C)C
Targets
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Sold for research purposes under agreement from Pfizer Inc.
Nirmatrelvir (CAS 2628280-40-8), also known as pf-07321332, functions as a potent inhibitor of the SARS-CoV-2 main protease (Mpro). This viral enzyme is essential for coronavirus replication because it cleaves viral polyproteins that are necessary for forming active replication complexes. Due to this mechanism of action, pfizer pf-07321332 has become an important compound in antiviral drug discovery and molecular virology research.
Researchers studying antiviral mechanisms often analyze the nirmatrelvir structure and nirmatrelvir chemical structure to understand how protease inhibition blocks viral replication. The compound has a well-defined molecular formula and stable physicochemical properties suitable for biochemical assays and cell-based experiments. Laboratories involved in pharmaceutical development and academic virology programs frequently buy pf-07321332, pf-07321332 buy, or buy nirmatrelvir as a reference molecule for antiviral screening studies.
Nirmatrelvir is widely used in research focused on coronavirus replication and antiviral drug development. By targeting the viral main protease, the compound allows scientists to explore mechanisms of viral protein processing and evaluate new antiviral inhibitors.
In vitro studies demonstrate that pf-07321332 pfizer potently inhibits SARS-CoV-2 main protease activity. This inhibition prevents cleavage of viral polyproteins, which are essential for viral replication. As a result, viral replication is significantly reduced in infected cell cultures. These properties make Nirmatrelvir a valuable reference compound in antiviral assay development.
In vivo research models investigating coronavirus infection have shown that inhibition of viral proteases can significantly reduce viral replication and disease progression. Research involving pfizer pf 07321332 contributes to understanding how protease inhibitors influence viral load and host response in infected organisms.
The biochemical activity of Nirmatrelvir is based on selective binding to the active site of the SARS-CoV-2 main protease. By blocking enzymatic cleavage of viral polyproteins, the compound interrupts viral replication and the formation of essential viral components required for infection.
Access to high-quality bioactive compounds is essential for modern pharmaceutical and academic research. Reliable suppliers provide validated molecules that enable scientists to investigate molecular targets, accelerate antiviral discovery programs, and support the development of innovative therapeutic strategies. Researchers conducting antiviral screening programs often compare multiple protease inhibitors to better understand viral enzyme inhibition and structure-activity relationships. In such studies, laboratories frequently search for reliable sources for nirmatrelvir buy in order to ensure consistent experimental quality and reproducible results across different assay systems.
SDS
NMV | PF-07321332 | nirmatrelvir | paxlovid
No data available
The compound has purity validated by NMR and/or LCMS methods.
1 mg
$37
2 mg
$39
5 mg
$41
10 mg
$43
15 mg
$45
20 mg
$48
25 mg
$53
30 mg
$55
35 mg
$58
40 mg
$60
45 mg
$63
50 mg
$65
75 mg
$68
100 mg
$POA
Quantity
1
Total amount
$ 41
NMV | PF-07321332 | nirmatrelvir | paxlovid
No data available
The compound has purity validated by NMR and/or LCMS methods.
Target activity features
It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.