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  1. Home
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  3. Irinotecan

Irinotecan

We provide 1 form of Irinotecan

Molecule smiles
ID
EBC-12141
Name

Irinotecan hydrochloirde

Properties
CAS:

100286-90-6

|

MW:

623.139

|

cLogP:

2.728

Description

Irinotecan is an antineoplastic enzyme inhibitor primarily used in the treatment of colorectal cancer. It is a derivative of camptothecin that inhibits the action of topoisomerase I. Irinotecan prevents religation of the DNA strand by binding to topoisomerase I-DNA complex, and causes double-strand DNA breakage and cell death.

Synonyms

CPT-11 | Campto | camptosar | irinotecan | irinotecan Hydrochloride | irinotecan hydrochloirde | irinotecan monohydrochloride

Description

Irinotecan is an antineoplastic enzyme inhibitor primarily used in the treatment of colorectal cancer. It is a derivative of camptothecin that inhibits the action of topoisomerase I. Irinotecan prevents religation of the DNA strand by binding to topoisomerase I-DNA complex, and causes double-strand DNA breakage and cell death.

Synonyms

CPT-11 | Campto | camptosar | irinotecan | irinotecan Hydrochloride | irinotecan hydrochloirde | irinotecan monohydrochloride

$43/5 mg

(EBC)

-

1

+

In Stock

Other forms:

EBC-17160
EBC-17160

CAS:97682-44-5

(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl [1,4'-bipiperidine]-1'-carboxylate
(19S)-10,19-diethyl-...
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0

+

Impurities and Related Compounds

We provide 2 compounds for Irinotecan

Molecule smiles
ID
EBC-11025
Description

Irinotecan Related Compound B

IUPAC Name

(19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione

Name

SN-38

CAS number

86639-52-3

MW

392.405

cLogP

1.974

$19/5 mg

(EBC)

In Stock

-

1

+
Molecule smiles
ID
EBC-17074
Description

Irinotecan Related Compound A

IUPAC Name

(19S)-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione

Name

(S)-10-Hydroxycamptothecin

CAS number

19685-09-7

MW

364.106

cLogP

0.946

$19/5 mg

(EBC)

In Stock

-

1

+