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Product details:
CAS
2621928-55-8
Purity
95%
MRTX1133 has high affinity for the G12D-specific mutant of KRAS (not other mutations of the protein). The compound is effective in preventing KRAS-dependent phosphorylation of ERK in cell culture and in mice.
Properties
Name
MRTX1133
Smiles
OC=1C=C(C=2N=CC=3C(=NC(OC[C@]45CCCN5C[C@H](F)C4)=NC3C2F)N6C[C@@H]7CC[C@H](C6)N7)C=8C(C#C)=C(F)C=CC8C1
Targets
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Target name
Target pX
Target action
doi
MRTX1133
No data available
The compound has purity validated by NMR and/or LCMS methods.
1 mg
$100
2 mg
$130
5 mg
$260
10 mg
$451
15 mg
$546
20 mg
$642
25 mg
$780
30 mg
$919
35 mg
$1058
40 mg
$1197
45 mg
$1283
50 mg
$1370
75 mg
$1820
100 mg
$POA
Quantity
1
Total amount
$ 260
MRTX1133
No data available
The compound has purity validated by NMR and/or LCMS methods.
Target activity features
It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.