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Product details:
CAS
1561178-17-3
Purity
95%
SGC0946 is a potent inhibitor of DOT1L (IC50 = 0.3 nM). It is over 100-fold selective over other PMTs.
Properties
Name
SGC0946
Smiles
CC(C)N(CCCNC(=O)NC=1C=CC(=CC1)C(C)(C)C)C[C@H]2O[C@H]([C@H](O)[C@@H]2O)N3C=C(Br)C=4C(N)=NC=NC34
Targets
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Target name
Target pX
Target action
doi
SDS
SGC0946
No data available
The compound has purity validated by NMR and/or LCMS methods.
1 mg
$80
2 mg
$82
5 mg
$87
10 mg
$114
15 mg
$153
20 mg
$191
25 mg
$210
30 mg
$231
35 mg
$250
40 mg
$270
45 mg
$291
50 mg
$329
75 mg
$492
100 mg
$POA
Quantity
1
Total amount
$ 87
SGC0946
No data available
The compound has purity validated by NMR and/or LCMS methods.
Target activity features
It should be emphasized that the product may be active against a larger number of targets than shown on the card. The information represented here refers to the targets with the largest value of pX or the targets with ΔpX less than 1.5 from the largest pX value.