Vigabatrin

Vigabatrin

Vigabatrin is an analog of gamma-aminobutyric acid, the main inhibitory neurotransmitter in the central nervous system. It used in the treatment of refractory seizures and infantile spasms. It irreversibly inhibits the enzyme responsible for GABA metabolism, thereby increasing levels of circulating GABA. Although administered as a racemic mixture, only the S(+) enantiomer is pharmacologically active.

4-amino-5-hexenoic acid | vigabatrin