Cycloserine

Cycloserine

Cycloserine is a broad-spectrum antibiotic used in the treatment of tuberculosis and certain urinary tract infections. Cycloserine is an analog of the amino acid D-alanine. It interferes with an early step in bacterial cell wall synthesis in the cytoplasm by competitive inhibition of two enzymes, L-alanine racemase, which forms D-alanine from L-alanine, and D-alanylalanine synthetase, which incorporates D-alanine into the pentapeptide necessary for peptidoglycan formation and bacterial cell wall synthesis.

D-Cycloserine | L-cycloserine | cycloserine