Teriflunomide

We provide 1 form of Teriflunomide

Molecule smiles
Name

Teriflunomide

Properties
CAS:

163451-81-8

|

MW:

270.062

|

cLogP:

2.132

Description

Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. Teriflunomide prevents pyrimidine synthesis by inhibiting the mitochondrial enzyme dihydroorotate dehydrogenase, and this may be involved in its immunomodulatory effect in MS.

Synonyms

2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide | A77 1726 | A771726 | N-(4-trifluoro-methylphenyl)-2-cyano-3-hydroxycrotonamide | aubagio | teriflunomide

Description

Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. Teriflunomide prevents pyrimidine synthesis by inhibiting the mitochondrial enzyme dihydroorotate dehydrogenase, and this may be involved in its immunomodulatory effect in MS.

Synonyms

2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide | A77 1726 | A771726 | N-(4-trifluoro-methylphenyl)-2-cyano-3-hydroxycrotonamide | aubagio | teriflunomide

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1

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In Stock

Impurities and Related Compounds

We provide 0 compound for Teriflunomide