Building on the legacy of nature’s medicine chest, our Library of Natural Product Derivatives and Analogs offers a powerful expansion of structural diversity beyond native compounds. These molecules are synthetically modified or inspired by known natural scaffolds, enhancing their pharmacokinetic properties, stability, and target specificity while preserving the unique biological richness of their origins.

Our collection of 30480 expertly designed compounds includes semi-synthetic derivatives, analogs, and bioisosteric variants aimed at improving efficacy and minimizing toxicity. This library bridges the gap between traditional natural products and modern medicinal chemistry—making it an ideal source for lead optimization, SAR studies, and phenotypic screening.

With annotated data of predicted targets, and drug-likeness, this library enables focused discovery in various areas. Whether you're seeking novel mechanisms or known frameworks with improved profiles, our library of analogs is a rich, rationally built resource tailored for translational research.

Related terms: natural products, modified natural products, small molecule derivatives, nature medicine, traditional medicine