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The Library of Psychoactive Drugs is a curated collection of compounds known for their ability to have a significant impact on human brain function. These substances affect a person's perception, mood, consciousness, or behavior. The library encompasses a range of psychoactive agents, including sedatives, hypnotics, antipsychotics, and antidepressants. This data can serve as a valuable resource in research on the neurological and behavioral effects of psychoactive compounds.
The Library of Psychoactive Drugs contains 132 molecules. The mechanisms of action and their effects on the CNS are known for all presented compounds.
Related terms: Catechol-O-methyltransferase, GPСR, 5-HT2A receptor, antipsychotics, neurotrophic receptor tyrosine kinase, GABA, antidepressants, butyrylcholinesterase, TRPM6.
Risperidone is a second-generation antipsychotic medication.
Granisetron is a serotonin 5-HT3 receptor antagonist.
Amoxapine is a tetracyclic antidepressant.
Sultopride is an atypical antipsychotic used for the treatment of schizophrenia.
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NoteAll the compounds with solubility below 10 mM are shipped as 2 mM solutions.
G protein-coupled receptors
48
48
Number of compounds
48
SLC6 neurotransmitter transporter family
9
9
Number of compounds
9
Catecholamine turnover
9
9
Number of compounds
9
Potassium channels
8
8
Number of compounds
8
Ligand-gated ion channels
8
8
Number of compounds
8
Sigma receptors
5
5
Number of compounds
5
Carbonic anhydrases
5
5
Number of compounds
5
Voltage-gated ion channels
4
4
Number of compounds
4
Cytochrome P450
3
3
Number of compounds
3
Receptor tyrosine kinases (RTKs)
3
3
Number of compounds
3
Wnt signaling pathway
3
3
Number of compounds
3
Oxidoreductases
2
2
Number of compounds
2
Nuclear hormone receptors
2
2
Number of compounds
2
Acetylcholine turnover
1
1
Number of compounds
1
GABA turnover
1
1
Number of compounds
1
Eicosanoid turnover
1
1
Number of compounds
1
Steroid hormone receptors
1
1
Number of compounds
1
SLC28 and SLC29 families of nucleoside transporters
1
1
Number of compounds
1
Catalytic receptors
1
1
Number of compounds
1
Chromatin modifying enzymes
1
1
Number of compounds
1
SLC22 family of organic cation and anion transporters
1
1
Number of compounds
1
Hydrolases
1
1
Number of compounds
1
Aryl hydrocarbon receptor complex
1
1
Number of compounds
1
SLC superfamily of solute carriers
1
1
Number of compounds
1
EBCL-0033