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EBCL-0027

Approved Drugs

FDA (U.S. Food and Drug Administration in the USA), EMA (European Medicines Agency in the European Union), NMPA (National Medical Products Administration in China), and PMDA (Pharmaceuticals and Medical Devices Agency in Japan) are major regulatory agencies ensuring the safety and efficacy of human drugs.

The library of Approved Drugs is composed of 1070 compounds certified by one or few leading pharmaceutical regulatory agencies.


Related terms: H1 receptor, D2 receptor, carbonic anhydrase, 5-HT2A receptor, acetylcholinesterase, COX-1, epidermal growth factor receptor, COX-2, D3 receptor

Library image center

Preplated options

Dry powder/solution (DMSO)Dry powder
Number of compounds1070
Comment

Highlights

Molecule highlight
EBC-03919CAS: 330784-47-9

Avanafil is a potent and highly selective phosphodiesterase-5 (PDE-5) inhibitor. It is used to treat erectile dysfunction

Molecule highlight
EBC-06851CAS: 3575-80-2

Melperone is an atypical antipsychotic that demonstrates antagonist activity at D 2 dopaminergic and 5-HT 2A serotonergic receptors

Molecule highlight
EBC-44276CAS: 526-18-1

Osalmid is a ribonucleotide reductase small subunit M2 targeting compound

Molecule highlight
EBC-03924CAS: 70374-39-9

Lornoxicam is a non-steroidal anti-inflammatory drug (NSAID). It potently inhibits both COX-1 and COX-2.

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Disclaimer

All our products are for research purpose only. Any personal or non-scientific use is strictly prohibited.

Note

All the compounds with solubility below 10 mM are shipped as 2 mM solutions.

Product Features

  • Approved Drugs Library is a set of 1070 bioactive molecules for HTS/HCS programs.
  • Comprehensive documentation with structures, trivial names, synonyms, activity coefficient values, types of action on target and references to original literature.
  • NMR and LCMS validated purity.
  • All the compounds are available in stock for hit follow-up.
  • The library is continuously updated.


Product Details

  • Format: 10 - 100 µL of 10 mM DMSO stock solutions; dry powders (1 mg);
  • Container: 384-well microplates;
  • Storage: - 18 °C;
  • Shipping: Dry ice.

Utility

  • High throughput screening (HTS);
  • High content screening (HCS);
  • Cherry picking.

Library Composition

Name
Occurrence in the library, times

H1 receptor

39

39

Number of compounds

39

D2 receptor

31

31

Number of compounds

31

COX-1

29

29

Number of compounds

29

carbonic anhydrase 2

26

26

Number of compounds

26

Kv11.1

24

24

Number of compounds

24

acetylcholinesterase (Cartwright blood group)

23

23

Number of compounds

23

5-HT2A receptor

23

23

Number of compounds

23

epidermal growth factor receptor

22

22

Number of compounds

22

D3 receptor

18

18

Number of compounds

18

Androgen receptor

18

18

Number of compounds

18

COX-2

18

18

Number of compounds

18

carbonic anhydrase 1

18

18

Number of compounds

18

CYP1A2

17

17

Number of compounds

17

ABCB1

17

17

Number of compounds

17

M1 receptor

17

17

Number of compounds

17

β2-adrenoceptor

14

14

Number of compounds

14

dihydrofolate reductase

14

14

Number of compounds

14

α1A-adrenoceptor

14

14

Number of compounds

14

carbonic anhydrase 12

14

14

Number of compounds

14

carbonic anhydrase 9

14

14

Number of compounds

14

CYP1A1

13

13

Number of compounds

13

SERT

13

13

Number of compounds

13

M2 receptor

13

13

Number of compounds

13

CYP2E1

12

12

Number of compounds

12

M3 receptor

12

12

Number of compounds

12

ABCG2

12

12

Number of compounds

12

Cav1.1

12

12

Number of compounds

12

α1B-adrenoceptor

11

11

Number of compounds

11

D1 receptor

11

11

Number of compounds

11

serine protease 1

11

11

Number of compounds

11

carbonic anhydrase 7

11

11

Number of compounds

11

α2A-adrenoceptor

10

10

Number of compounds

10

Organic anion transporter 3

10

10

Number of compounds

10

tubulin alpha 1a

10

10

Number of compounds

10

Glucocorticoid receptor

10

10

Number of compounds

10

Cav1.2

10

10

Number of compounds

10

erb-b2 receptor tyrosine kinase 2

10

10

Number of compounds

10

carbonic anhydrase 14

10

10

Number of compounds

10

α2B-adrenoceptor

9

9

Number of compounds

9

Progesterone receptor

9

9

Number of compounds

9

kinase insert domain receptor

9

9

Number of compounds

9

Monoamine oxidase A

9

9

Number of compounds

9

M4 receptor

9

9

Number of compounds

9

carbonic anhydrase 4

9

9

Number of compounds

9

β1-adrenoceptor

8

8

Number of compounds

8

DAT

8

8

Number of compounds

8

sigma non-opioid intracellular receptor 1

8

8

Number of compounds

8

Peroxisome proliferator-activated receptor-γ

8

8

Number of compounds

8

Organic cation transporter 1

8

8

Number of compounds

8

ATP-binding cassette, sub-family C (CFTR/MRP), member 8

8

8

Number of compounds

8

5-HT3A

8

8

Number of compounds

8

5-HT6 receptor

8

8

Number of compounds

8

5-HT1B receptor

8

8

Number of compounds

8

Kv9.1

7

7

Number of compounds

7

α2C-adrenoceptor

7

7

Number of compounds

7

NET

7

7

Number of compounds

7

myeloperoxidase

7

7

Number of compounds

7

sepiapterin reductase

7

7

Number of compounds

7

platelet derived growth factor receptor alpha

7

7

Number of compounds

7

Monoamine oxidase B

7

7

Number of compounds

7

amine oxidase copper containing 3

7

7

Number of compounds

7

Kir6.2

7

7

Number of compounds

7

GABAA receptor α1 subunit

7

7

Number of compounds

7

GABAA receptor β2 subunit

7

7

Number of compounds

7

GABAA receptor δ subunit

7

7

Number of compounds

7

AT1 receptor

7

7

Number of compounds

7

D4 receptor

6

6

Number of compounds

6

α1D-adrenoceptor

6

6

Number of compounds

6

Organic anion transporter 1

6

6

Number of compounds

6

Organic cation transporter 3

6

6

Number of compounds

6

CYP51A1

6

6

Number of compounds

6

histone deacetylase 1

6

6

Number of compounds

6

Mineralocorticoid receptor

6

6

Number of compounds

6

platelet derived growth factor receptor beta

6

6

Number of compounds

6

ret proto-oncogene

6

6

Number of compounds

6

CoV 3C-like (main) protease

6

6

Number of compounds

6

Peroxisome proliferator-activated receptor-α

6

6

Number of compounds

6

M5 receptor

6

6

Number of compounds

6

butyrylcholinesterase

6

6

Number of compounds

6

KNa1.1

6

6

Number of compounds

6

Janus kinase 2

6

6

Number of compounds

6

carbonic anhydrase 13

6

6

Number of compounds

6

Angiotensin-converting enzyme

6

6

Number of compounds

6

A3 receptor

6

6

Number of compounds

6

5-HT7 receptor

6

6

Number of compounds

6

5-HT2B receptor

6

6

Number of compounds

6

5-HT1D receptor

6

6

Number of compounds

6

5-HT1A receptor

6

6

Number of compounds

6

Nav1.5

5

5

Number of compounds

5

Nav1.7

5

5

Number of compounds

5

TRPV1

5

5

Number of compounds

5

TRPA1

5

5

Number of compounds

5

Multidrug and toxin extrusion

5

5

Number of compounds

5

Pregnane X receptor

5

5

Number of compounds

5

ABL proto-oncogene 1, non-receptor tyrosine kinase

5

5

Number of compounds

5

fms related receptor tyrosine kinase 3

5

5

Number of compounds

5

phosphodiesterase 5A

5

5

Number of compounds

5

AKR1C3

5

5

Number of compounds

5

OATP1B1

5

5

Number of compounds

5

OATP1B3

5

5

Number of compounds

5

GluN2D

5

5

Number of compounds

5

MDM2 proto-oncogene

5

5

Number of compounds

5

MC3 receptor

5

5

Number of compounds

5

glycine receptor α1 subunit

5

5

Number of compounds

5

farnesyl diphosphate synthase

5

5

Number of compounds

5

Janus kinase 1

5

5

Number of compounds

5

Insulin receptor

5

5

Number of compounds

5

H2 receptor

5

5

Number of compounds

5

Estrogen receptor-β

5

5

Number of compounds

5

dipeptidyl peptidase 4

5

5

Number of compounds

5

CYP17A1

5

5

Number of compounds

5

CFTR

5

5

Number of compounds

5

CCR5

5

5

Number of compounds

5

A2A receptor

5

5

Number of compounds

5

A1 receptor

5

5

Number of compounds

5

5-HT2C receptor

5

5

Number of compounds

5

heat shock protein 90 beta family member 1

4

4

Number of compounds

4

Nav1.2

4

4

Number of compounds

4

xanthine dehydrogenase

4

4

Number of compounds

4

topoisomerase (DNA) I mitochondrial

4

4

Number of compounds

4

Organic cation/carnitine transporter 2

4

4

Number of compounds

4

OATP1A2

4

4

Number of compounds

4

epoxide hydrolase 2

4

4

Number of compounds

4

hydroxymethylglutaryl-CoA reductase

4

4

Number of compounds

4

protein tyrosine kinase 2

4

4

Number of compounds

4

Arginase I

4

4

Number of compounds

4

fms related receptor tyrosine kinase 1

4

4

Number of compounds

4

fms related receptor tyrosine kinase 4

4

4

Number of compounds

4

Organic cation transporter 2

4

4

Number of compounds

4

Nav1.1

4

4

Number of compounds

4

CYP19A1

4

4

Number of compounds

4

Aryl hydrocarbon receptor

4

4

Number of compounds

4

SRC proto-oncogene, non-receptor tyrosine kinase

4

4

Number of compounds

4

GluN2C

4

4

Number of compounds

4

KCa1.1

4

4

Number of compounds

4

ALK receptor tyrosine kinase

4

4

Number of compounds

4

Kv7.1

4

4

Number of compounds

4

CXCR4

4

4

Number of compounds

4

carboxylesterase 1

4

4

Number of compounds

4

CaS receptor

4

4

Number of compounds

4

μ receptor

3

3

Number of compounds

3

σ2

3

3

Number of compounds

3

transthyretin

3

3

Number of compounds

3

tyrosinase

3

3

Number of compounds

3

phosphodiesterase 4B

3

3

Number of compounds

3

Thyroid hormone receptor-α

3

3

Number of compounds

3

TA1 receptor

3

3

Number of compounds

3

squalene monooxygenase

3

3

Number of compounds

3

Sodium/glucose cotransporter 2

3

3

Number of compounds

3

SMO

3

3

Number of compounds

3

CYP11B2

3

3

Number of compounds

3

5-LOX

3

3

Number of compounds

3

Retinoic acid receptor-β

3

3

Number of compounds

3

MMP2

3

3

Number of compounds

3

discoidin domain receptor tyrosine kinase 2

3

3

Number of compounds

3

discoidin domain receptor tyrosine kinase 1

3

3

Number of compounds

3

LCK proto-oncogene, Src family tyrosine kinase

3

3

Number of compounds

3

coagulation factor X

3

3

Number of compounds

3

H-PGDS

3

3

Number of compounds

3

Organic anion transporter 2

3

3

Number of compounds

3

nicotinic acetylcholine receptor α7 subunit

3

3

Number of compounds

3

Vesicular monoamine transporter 2

3

3

Number of compounds

3

leukocyte receptor tyrosine kinase

3

3

Number of compounds

3

c-ros oncogene 1, receptor tyrosine kinase

3

3

Number of compounds

3

CYP7B1

3

3

Number of compounds

3

Kir6.1

3

3

Number of compounds

3

Janus kinase 3

3

3

Number of compounds

3

integrin, alpha M subunit (complement component 3 receptor 3 subunit)

3

3

Number of compounds

3

AKT serine/threonine kinase 1

3

3

Number of compounds

3

GPRC6 receptor

3

3

Number of compounds

3

GPR35

3

3

Number of compounds

3

GPBA receptor

3

3

Number of compounds

3

synaptic vesicle glycoprotein 2A

3

3

Number of compounds

3

GABAA receptor α2 subunit

3

3

Number of compounds

3

GABAA receptor α5 subunit

3

3

Number of compounds

3

GABAA receptor β3 subunit

3

3

Number of compounds

3

GABAA receptor γ2 subunit

3

3

Number of compounds

3

B-Raf proto-oncogene, serine/threonine kinase

3

3

Number of compounds

3

cyclin dependent kinase 7

3

3

Number of compounds

3

CysLT1 receptor

3

3

Number of compounds

3

CYP27A1

3

3

Number of compounds

3

CYP1B1

3

3

Number of compounds

3

CXCR1

3

3

Number of compounds

3

coagulation factor II, thrombin

3

3

Number of compounds

3

CD4

3

3

Number of compounds

3

5-HT4 receptor

3

3

Number of compounds

3

5-HT3B

3

3

Number of compounds

3

κ receptor

2

2

Number of compounds

2

Kv4.3

2

2

Number of compounds

2

β3-adrenoceptor

2

2

Number of compounds

2

V2 receptor

2

2

Number of compounds

2

TRPM8

2

2

Number of compounds

2

aldehyde dehydrogenase 2 family member

2

2

Number of compounds

2

fatty acid binding protein 2

2

2

Number of compounds

2

TLR7

2

2

Number of compounds

2

MATE2

2

2

Number of compounds

2

thyroid peroxidase

2

2

Number of compounds

2

steroid 5 alpha-reductase 2

2

2

Number of compounds

2

Equilibrative nucleoside transporter 1

2

2

Number of compounds

2

Equilibrative nucleoside transporter 2

2

2

Number of compounds

2

Sodium/glucose cotransporter 1

2

2

Number of compounds

2

signal transducer and activator of transcription 3

2

2

Number of compounds

2

Retinoic acid receptor-γ

2

2

Number of compounds

2

Haem oxygenase 1

2

2

Number of compounds

2

protein kinase C iota

2

2

Number of compounds

2

proteasome 20S subunit beta 5

2

2

Number of compounds

2

histone deacetylase 6

2

2

Number of compounds

2

MMP7

2

2

Number of compounds

2

colony stimulating factor 1 receptor

2

2

Number of compounds

2

phosphodiesterase 4D

2

2

Number of compounds

2

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma

2

2

Number of compounds

2

pancreatic lipase

2

2

Number of compounds

2

PAF receptor

2

2

Number of compounds

2

P2Y12 receptor

2

2

Number of compounds

2

NK1 receptor

2

2

Number of compounds

2

nicotinic acetylcholine receptor α4 subunit

2

2

Number of compounds

2

nicotinic acetylcholine receptor β2 subunit

2

2

Number of compounds

2

Neutral endopeptidase

2

2

Number of compounds

2

neurotrophic receptor tyrosine kinase 1

2

2

Number of compounds

2

S-Adenosylhomocysteine hydrolase

2

2

Number of compounds

2

MT1 receptor

2

2

Number of compounds

2

MT2 receptor

2

2

Number of compounds

2

mitogen-activated protein kinase kinase 1

2

2

Number of compounds

2

mGlu1 receptor

2

2

Number of compounds

2

KCa3.1

2

2

Number of compounds

2

Methionyl aminopeptidase 2

2

2

Number of compounds

2

Methionyl aminopeptidase 1

2

2

Number of compounds

2

MET proto-oncogene, receptor tyrosine kinase

2

2

Number of compounds

2

H3 receptor

2

2

Number of compounds

2

Nav1.4

2

2

Number of compounds

2

cyclin dependent kinase 1

2

2

Number of compounds

2

ABCC9

2

2

Number of compounds

2

Inducible NOS

2

2

Number of compounds

2

tyrosine kinase 2

2

2

Number of compounds

2

integrin, alpha 4 subunit (antigen CD49D, alpha 4 subunit of VLA-4 receptor)

2

2

Number of compounds

2

histone deacetylase 8

2

2

Number of compounds

2

histone deacetylase 2

2

2

Number of compounds

2

histone deacetylase 3

2

2

Number of compounds

2

histone deacetylase 5

2

2

Number of compounds

2

Farnesoid X receptor

2

2

Number of compounds

2

checkpoint kinase 1

2

2

Number of compounds

2

GluN2B

2

2

Number of compounds

2

Kv3.1

2

2

Number of compounds

2

GABAB2

2

2

Number of compounds

2

GABAA receptor α4 subunit

2

2

Number of compounds

2

GABAA receptor β1 subunit

2

2

Number of compounds

2

GABAA receptor α3 subunit

2

2

Number of compounds

2

Nav1.8

2

2

Number of compounds

2

FPR1

2

2

Number of compounds

2

FP receptor

2

2

Number of compounds

2

Folate hydrolase (prostate-specific membrane antigen) 1

2

2

Number of compounds

2

Raf-1 proto-oncogene, serine/threonine kinase

2

2

Number of compounds

2

FFA1 receptor

2

2

Number of compounds

2

CYP11A1

2

2

Number of compounds

2

erb-b2 receptor tyrosine kinase 4

2

2

Number of compounds

2

BLK proto-oncogene, Src family tyrosine kinase

2

2

Number of compounds

2

BMX non-receptor tyrosine kinase

2

2

Number of compounds

2

Bruton tyrosine kinase

2

2

Number of compounds

2

TXK tyrosine kinase

2

2

Number of compounds

2

EP2 receptor

2

2

Number of compounds

2

endoplasmic reticulum to nucleus signaling 1

2

2

Number of compounds

2

DNA methyltransferase 1

2

2

Number of compounds

2

CYP11B1

2

2

Number of compounds

2

cyclin dependent kinase 9

2

2

Number of compounds

2

cyclin dependent kinase 2

2

2

Number of compounds

2

cyclin dependent kinase 4

2

2

Number of compounds

2

mitogen-activated protein kinase kinase kinase 3

2

2

Number of compounds

2

CCR2

2

2

Number of compounds

2

CB1 receptor

2

2

Number of compounds

2

Catechol-O-methyltransferase

2

2

Number of compounds

2

carbonic anhydrase 5A

2

2

Number of compounds

2

AT2 receptor

2

2

Number of compounds

2

Angiotensin-converting enzyme 2

2

2

Number of compounds

2

ABCC4

2

2

Number of compounds

2

ABCB11

2

2

Number of compounds

2

A2B receptor

2

2

Number of compounds

2

5-ht1e receptor

2

2

Number of compounds

2

δ receptor

1

1

Number of compounds

1

NTS1 receptor

1

1

Number of compounds

1

zeta chain of T cell receptor associated protein kinase 70

1

1

Number of compounds

1

Y4 receptor

1

1

Number of compounds

1

Vitamin D receptor

1

1

Number of compounds

1

V1A receptor

1

1

Number of compounds

1

Glucose transporter 1

1

1

Number of compounds

1

Peptide transporter 2

1

1

Number of compounds

1

tumor necrosis factor receptor 1

1

1

Number of compounds

1

glutaminase

1

1

Number of compounds

1

TRPV2

1

1

Number of compounds

1

TRPM3

1

1

Number of compounds

1

TRPM7

1

1

Number of compounds

1

TRH-specific aminopeptidase

1

1

Number of compounds

1

TP receptor

1

1

Number of compounds

1

TLR8

1

1

Number of compounds

1

TLR2

1

1

Number of compounds

1

Thyroid hormone receptor-β

1

1

Number of compounds

1

Retinoid X receptor-α

1

1

Number of compounds

1

TAS2R38

1

1

Number of compounds

1

succinate receptor

1

1

Number of compounds

1

Na+/dicarboxylate cotransporter 3

1

1

Number of compounds

1

Sodium/nucleoside cotransporter 1

1

1

Number of compounds

1

Solute carrier family 28 member 3

1

1

Number of compounds

1

Equilibrative nucleoside transporter 3

1

1

Number of compounds

1

cytidine deaminase

1

1

Number of compounds

1

serine palmitoyltransferase long chain base subunit 1

1

1

Number of compounds

1

S1P1 receptor

1

1

Number of compounds

1

S1P5 receptor

1

1

Number of compounds

1

RyR2

1

1

Number of compounds

1

RTP Type A

1

1

Number of compounds

1

RTP Type E

1

1

Number of compounds

1

RTP Type S

1

1

Number of compounds

1

Vesicular glutamate transporter 3

1

1

Number of compounds

1

Rho associated coiled-coil containing protein kinase 2

1

1

Number of compounds

1

retinol binding protein 1

1

1

Number of compounds

1

CYP27C1

1

1

Number of compounds

1

Ornithine decarboxylase

1

1

Number of compounds

1

phosphodiesterase 8A

1

1

Number of compounds

1

Retinoic acid receptor-α

1

1

Number of compounds

1

renin

1

1

Number of compounds

1

3-Mercaptopyruvate sulfurtransferase

1

1

Number of compounds

1

proteasome 20S subunit beta 2

1

1

Number of compounds

1

proteasome 20S subunit beta 1

1

1

Number of compounds

1

proteasome 20S subunit beta 8

1

1

Number of compounds

1

proteasome 20S subunit beta 9

1

1

Number of compounds

1

prolyl endopeptidase

1

1

Number of compounds

1

MMP3

1

1

Number of compounds

1

MMP8

1

1

Number of compounds

1

p21 (RAC1) activated kinase 1

1

1

Number of compounds

1

fibroblast growth factor receptor 2

1

1

Number of compounds

1

fibroblast growth factor receptor 1

1

1

Number of compounds

1

fibroblast growth factor receptor 3

1

1

Number of compounds

1

maternal embryonic leucine zipper kinase

1

1

Number of compounds

1

YES proto-oncogene 1, Src family tyrosine kinase

1

1

Number of compounds

1

phosphodiesterase 11A

1

1

Number of compounds

1

phosphodiesterase 4A

1

1

Number of compounds

1

phosphodiesterase 4C

1

1

Number of compounds

1

phosphodiesterase 10A

1

1

Number of compounds

1

phosphodiesterase 3A

1

1

Number of compounds

1

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

1

1

Number of compounds

1

inosine monophosphate dehydrogenase 1

1

1

Number of compounds

1

inosine monophosphate dehydrogenase 2

1

1

Number of compounds

1

PAR1

1

1

Number of compounds

1

lipase G, endothelial type

1

1

Number of compounds

1

Diacylglycerol lipase α

1

1

Number of compounds

1

P2X1

1

1

Number of compounds

1

Organic cation/carnitine transporter 1

1

1

Number of compounds

1

L-PGDS

1

1

Number of compounds

1

mitochondrial pyruvate carrier 1

1

1

Number of compounds

1

NPFF1 receptor

1

1

Number of compounds

1

NPC1 like intracellular cholesterol transporter 1

1

1

Number of compounds

1

nicotinic acetylcholine receptor α3 subunit

1

1

Number of compounds

1

nicotinic acetylcholine receptor β4 subunit

1

1

Number of compounds

1

Nav1.6

1

1

Number of compounds

1

protein arginine methyltransferase 5

1

1

Number of compounds

1

Plasma membrane monoamine transporter

1

1

Number of compounds

1

motilin receptor

1

1

Number of compounds

1

MMP9

1

1

Number of compounds

1

legumain

1

1

Number of compounds

1

choline O-acetyltransferase

1

1

Number of compounds

1

MMP14

1

1

Number of compounds

1

MMP12

1

1

Number of compounds

1

mitogen-activated protein kinase 1

1

1

Number of compounds

1

mitogen-activated protein kinase 8

1

1

Number of compounds

1

mGlu6 receptor

1

1

Number of compounds

1

Excitatory amino acid transporter 4

1

1

Number of compounds

1

KCa2.1

1

1

Number of compounds

1

TRPC5

1

1

Number of compounds

1

Cav2.2

1

1

Number of compounds

1

Cystine/glutamate transporter

1

1

Number of compounds

1

phosphatase and tensin homolog

1

1

Number of compounds

1

MC4 receptor

1

1

Number of compounds

1

MC5 receptor

1

1

Number of compounds

1

nicotinic acetylcholine receptor α1 subunit

1

1

Number of compounds

1

nicotinic acetylcholine receptor β1 subunit

1

1

Number of compounds

1

nicotinic acetylcholine receptor δ subunit

1

1

Number of compounds

1

nicotinic acetylcholine receptor ε subunit

1

1

Number of compounds

1

glycine receptor β subunit

1

1

Number of compounds

1

lanosterol synthase

1

1

Number of compounds

1

L-Arginine decarboxylase

1

1

Number of compounds

1

indoleamine 2,3-dioxygenase 1

1

1

Number of compounds

1

Kv3.3

1

1

Number of compounds

1

Kv3.4

1

1

Number of compounds

1

ZAK sterile alpha motif and leucine zipper containing kinase AZK

1

1

Number of compounds

1

Kv1.3

1

1

Number of compounds

1

Cx46

1

1

Number of compounds

1

F-type ATPase α subunit

1

1

Number of compounds

1

Kir3.4

1

1

Number of compounds

1

OATP2B1

1

1

Number of compounds

1

kelch like ECH-associated protein 1

1

1

Number of compounds

1

4-aminobutyrate aminotransferase

1

1

Number of compounds

1

Endothelial NOS

1

1

Number of compounds

1

kallikrein related peptidase 7

1

1

Number of compounds

1

K2P3.1

1

1

Number of compounds

1

K2P2.1

1

1

Number of compounds

1

Nav1.9

1

1

Number of compounds

1

Interleukin-4 receptor subunit α

1

1

Number of compounds

1

Interleukin-6 receptor

1

1

Number of compounds

1

Interferon-γ receptor

1

1

Number of compounds

1

FKBP prolyl isomerase 1A

1

1

Number of compounds

1

L-Aromatic amino-acid decarboxylase

1

1

Number of compounds

1

integrin, alpha 1 subunit

1

1

Number of compounds

1

integrin, alpha 2 subunit (CD49B, alpha 2 subunit of VLA-2 receptor)

1

1

Number of compounds

1

integrin, beta 3 subunit (platelet glycoprotein IIIa, antigen CD61)

1

1

Number of compounds

1

Fatty acid amide hydrolase

1

1

Number of compounds

1

TLR9

1

1

Number of compounds

1

EPH receptor B1

1

1

Number of compounds

1

Constitutive androstane receptor

1

1

Number of compounds

1

mGlu2 receptor

1

1

Number of compounds

1

mGlu3 receptor

1

1

Number of compounds

1

Sodium/bile acid and sulphated solute cotransporter 2

1

1

Number of compounds

1

GnRH1 receptor

1

1

Number of compounds

1

RAR-related orphan receptor-γ

1

1

Number of compounds

1

ATR serine/threonine kinase

1

1

Number of compounds

1

glutathione-disulfide reductase

1

1

Number of compounds

1

glutaminyl-peptide cyclotransferase

1

1

Number of compounds

1

Neuronal NOS

1

1

Number of compounds

1

nicotinic acetylcholine receptor α9 subunit

1

1

Number of compounds

1

nicotinic acetylcholine receptor α10 subunit

1

1

Number of compounds

1

TRPM2

1

1

Number of compounds

1

GLP-1 receptor

1

1

Number of compounds

1

geranylgeranyl diphosphate synthase

1

1

Number of compounds

1

MMP13

1

1

Number of compounds

1

GAT1

1

1

Number of compounds

1

GABAA receptor γ1 subunit

1

1

Number of compounds

1

transforming growth factor beta receptor 1

1

1

Number of compounds

1

Transforming growth factor β receptor

1

1

Number of compounds

1

GABAA receptor α6 subunit

1

1

Number of compounds

1

ClC-1

1

1

Number of compounds

1

glycogen synthase kinase 3 beta

1

1

Number of compounds

1

death associated protein kinase 1

1

1

Number of compounds

1

death associated protein kinase 3

1

1

Number of compounds

1

doublecortin like kinase 3

1

1

Number of compounds

1

cyclin G associated kinase

1

1

Number of compounds

1

mitogen-activated protein kinase kinase kinase 8

1

1

Number of compounds

1

serine/threonine kinase 16

1

1

Number of compounds

1

LYN proto-oncogene, Src family tyrosine kinase

1

1

Number of compounds

1

spleen associated tyrosine kinase

1

1

Number of compounds

1

FFA2 receptor

1

1

Number of compounds

1

FFA3 receptor

1

1

Number of compounds

1

fatty acid binding protein 5

1

1

Number of compounds

1

Fatty acid amide hydrolase-2

1

1

Number of compounds

1

ETA receptor

1

1

Number of compounds

1

ETB receptor

1

1

Number of compounds

1

Estrogen-related receptor-γ

1

1

Number of compounds

1

Estrogen-related receptor-α

1

1

Number of compounds

1

receptor interacting serine/threonine kinase 2

1

1

Number of compounds

1

AXL receptor tyrosine kinase

1

1

Number of compounds

1

tec protein tyrosine kinase

1

1

Number of compounds

1

PLCγ2

1

1

Number of compounds

1

ABCC5

1

1

Number of compounds

1

Proton-coupled folate transporter

1

1

Number of compounds

1

Tyrosine aminotransferase

1

1

Number of compounds

1

Endothelin-converting enzyme 1

1

1

Number of compounds

1

ENaC α

1

1

Number of compounds

1

ENaC β

1

1

Number of compounds

1

ENaC γ

1

1

Number of compounds

1

Prolylcarboxypeptidase

1

1

Number of compounds

1

Dipeptidyl-peptidase 7

1

1

Number of compounds

1

DP1 receptor

1

1

Number of compounds

1

IP receptor

1

1

Number of compounds

1

Dipeptidase 1

1

1

Number of compounds

1

CYP8B1

1

1

Number of compounds

1

DNA (cytosine-5-)-methyltransferase 3α

1

1

Number of compounds

1

cyclin dependent kinase 6

1

1

Number of compounds

1

cyclin dependent kinase 5

1

1

Number of compounds

1

Cx43

1

1

Number of compounds

1

hydroxysteroid 11-beta dehydrogenase 1

1

1

Number of compounds

1

coagulation factor IX

1

1

Number of compounds

1

vitamin K epoxide reductase complex subunit 1

1

1

Number of compounds

1

kallikrein B1

1

1

Number of compounds

1

plasminogen activator, tissue type

1

1

Number of compounds

1

ClC-2

1

1

Number of compounds

1

FGR proto-oncogene, Src family tyrosine kinase

1

1

Number of compounds

1

WEE1 G2 checkpoint kinase

1

1

Number of compounds

1

CoV Spike glycoprotein

1

1

Number of compounds

1

CYP21A2

1

1

Number of compounds

1

CB2 receptor

1

1

Number of compounds

1

Cav3.1

1

1

Number of compounds

1

CatSper1

1

1

Number of compounds

1

cathepsin L

1

1

Number of compounds

1

lysyl oxidase like 2

1

1

Number of compounds

1

CoV Non-structural protein 8

1

1

Number of compounds

1

CaCC

1

1

Number of compounds

1

beta-secretase 1

1

1

Number of compounds

1

15-LOX-1

1

1

Number of compounds

1

AP2 associated kinase 1

1

1

Number of compounds

1

embryonic ectoderm development

1

1

Number of compounds

1

AMP kinase

1

1

Number of compounds

1

Aminopeptidase N

1

1

Number of compounds

1

Arginyl aminopeptidase

1

1

Number of compounds

1

Leucine aminopeptidase 3

1

1

Number of compounds

1

Adenosine deaminase

1

1

Number of compounds

1

ADAM17

1

1

Number of compounds

1

activin A receptor type IL

1

1

Number of compounds

1

neurotrophic receptor tyrosine kinase 2

1

1

Number of compounds

1

neurotrophic receptor tyrosine kinase 3

1

1

Number of compounds

1

mitogen-activated protein kinase 10

1

1

Number of compounds

1

dihydropyrimidine dehydrogenase

1

1

Number of compounds

1

C-terminal Src kinase

1

1

Number of compounds

1

FER tyrosine kinase

1

1

Number of compounds

1

ubiquitin specific peptidase 5

1

1

Number of compounds

1

V-type ATPase V1 motor A subunit

1

1

Number of compounds

1

Alanine/serine/cysteine transporter 2

1

1

Number of compounds

1

integrin, alpha 5 subunit (fibronectin receptor, alpha polypeptide)

1

1

Number of compounds

1

integrin, beta 1 subunit (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)

1

1

Number of compounds

1

mPGES1

1

1

Number of compounds

1

PLA2-G5

1

1

Number of compounds

1

CoV Envelope protein

1

1

Number of compounds

1

casein kinase 2, alpha 1 polypeptide subunit

1

1

Number of compounds

1

DNA topoisomerase I

1

1

Number of compounds

1

DNA topoisomerase II alpha

1

1

Number of compounds

1

ABCC1

1

1

Number of compounds

1

ABCA1

1

1

Number of compounds

1

GABAB1

1

1

Number of compounds

1

oxoglutarate receptor

1

1

Number of compounds

1

protein kinase AMP-activated catalytic subunit alpha 2

1

1

Number of compounds

1

protein kinase AMP-activated non-catalytic subunit beta 1

1

1

Number of compounds

1

protein kinase AMP-activated non-catalytic subunit gamma 1

1

1

Number of compounds

1

Adenosine kinase

1

1

Number of compounds

1

nicotinic acetylcholine receptor α6 subunit

1

1

Number of compounds

1

5-HT3AB

1

1

Number of compounds

1

G protein subunit alpha q

1

1

Number of compounds

1

5-HT1F receptor

1

1

Number of compounds

1

4-hydroxyphenylpyruvate dioxygenase

1

1

Number of compounds

1

Show all