Compound libraries
Products
EBC main page
Search
Impurities
Chemical probes
Contact
Services
© 2026 Copyright Enamine
Back
Immuno-oncology is a trend in immunotherapy, which is directed at the stimulation of the immune system response against cancer cells. Normally the human immune system destroys cancer cells in the body, but cancer cells adapt and mutate in some cases, successfully camouflaging from the immune system. This fact allows tumors to grow and threaten the organism. Classical cancer immunotherapy agents are modified T-cells that target tumors, or antibody-based species that target the immune checkpoint cascades. However, small molecules acting on intracellular molecular targets, that affect immune response against cancer cells, are also an important tool for cancer immunology.
Cancer Immunology Related Ligands Library contains 1823 small ligands, some representative molecules are given below: Gefapixant, P2X3 receptor antagonist; ABX-1431, MAG lipase inhibitor; TGX115, PI3 kinase inhibitor; Ticagrelor, P2Y12 platelet inhibitor.
Related terms: A1 receptor, epoxide hydrolase, A2A, A3 receptor, fatty acid amide hydrolase, acetylcholinesterase, butyrylcholinesterase, carboxylesterase, Janus kinase
Immunosuppressive cells and related molecular targets in tumor microenvironment (Created by BioRender.com)
Gefapixant, P2X3 receptor antagonist EBC-08759
ABX-1431, MAG lipase inhibitor EBC-07964
TGX115, PI3 kinase inhibitor EBC-12379
Ticagrelor, P2Y12 platelet inhibitor EBC-12279
We propose the complete list of Services powered by Enamine
All our products are for research purpose only. Any personal or non-scientific use is strictly prohibited.
NoteAll the compounds with solubility below 10 mM are shipped as 2 mM solutions.
A1 receptor
61
61
Number of compounds
61
epoxide hydrolase 2
57
57
Number of compounds
57
A2A receptor
54
54
Number of compounds
54
A3 receptor
46
46
Number of compounds
46
Fatty acid amide hydrolase
40
40
Number of compounds
40
acetylcholinesterase (Cartwright blood group)
39
39
Number of compounds
39
butyrylcholinesterase
33
33
Number of compounds
33
carboxylesterase 1
28
28
Number of compounds
28
Janus kinase 2
17
17
Number of compounds
17
interleukin 1 receptor associated kinase 4
15
15
Number of compounds
15
Janus kinase 1
15
15
Number of compounds
15
P2X7
15
15
Number of compounds
15
Monoacylglycerol lipase
14
14
Number of compounds
14
tyrosine kinase 2
12
12
Number of compounds
12
signal transducer and activator of transcription 3
12
12
Number of compounds
12
Janus kinase 3
11
11
Number of compounds
11
indoleamine 2,3-dioxygenase 1
10
10
Number of compounds
10
CXCR1
7
7
Number of compounds
7
Arginase I
6
6
Number of compounds
6
CXCR4
6
6
Number of compounds
6
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
6
6
Number of compounds
6
A2B receptor
5
5
Number of compounds
5
DP2 receptor
5
5
Number of compounds
5
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5
5
Number of compounds
5
pancreatic lipase
4
4
Number of compounds
4
EP2 receptor
4
4
Number of compounds
4
phosphoinositide-3-kinase regulatory subunit 1
4
4
Number of compounds
4
TP receptor
4
4
Number of compounds
4
P2Y12 receptor
3
3
Number of compounds
3
activin A receptor type 1B
3
3
Number of compounds
3
CCR5
3
3
Number of compounds
3
CCR2
3
3
Number of compounds
3
EP4 receptor
3
3
Number of compounds
3
Interleukin-2 receptor
3
3
Number of compounds
3
Interleukin 21 receptor
3
3
Number of compounds
3
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
3
3
Number of compounds
3
Leukotriene A4 hydrolase
3
3
Number of compounds
3
TLR2
3
3
Number of compounds
3
transforming growth factor beta receptor 2
3
3
Number of compounds
3
CCR1
2
2
Number of compounds
2
CXCR2
2
2
Number of compounds
2
Diacylglycerol lipase α
2
2
Number of compounds
2
PLA2-G7
2
2
Number of compounds
2
DP1 receptor
2
2
Number of compounds
2
Interleukin-3 receptor
2
2
Number of compounds
2
tryptophan 2,3-dioxygenase
2
2
Number of compounds
2
phosphatidylinositol 3-kinase catalytic subunit type 3
2
2
Number of compounds
2
Interleukin-4 receptor subunit α
2
2
Number of compounds
2
Interleukin-13 receptor subunit α1
2
2
Number of compounds
2
Interleukin 23 receptor
2
2
Number of compounds
2
Eythropoietin receptor
2
2
Number of compounds
2
Granulocyte colony-stimulating factor receptor
2
2
Number of compounds
2
Interferon-γ receptor
2
2
Number of compounds
2
Interleukin-10 receptor
2
2
Number of compounds
2
Interleukin-12 receptor
2
2
Number of compounds
2
Interleukin-7 receptor
2
2
Number of compounds
2
Interleukin-15 receptor
2
2
Number of compounds
2
Interleukin-6 receptor
2
2
Number of compounds
2
Interleukin-27 receptor
2
2
Number of compounds
2
Thrombopoietin receptor
2
2
Number of compounds
2
P2X1
2
2
Number of compounds
2
P2X4
2
2
Number of compounds
2
TLR4
2
2
Number of compounds
2
TLR1
2
2
Number of compounds
2
TLR7
2
2
Number of compounds
2
phosphatidylinositol 4-kinase alpha
1
1
Number of compounds
1
CCR3
1
1
Number of compounds
1
CCR4
1
1
Number of compounds
1
CCR7
1
1
Number of compounds
1
CXCR3
1
1
Number of compounds
1
ACKR3
1
1
Number of compounds
1
Diacylglycerol lipase β
1
1
Number of compounds
1
lipase G, endothelial type
1
1
Number of compounds
1
IP receptor
1
1
Number of compounds
1
Interferon γ receptor 1
1
1
Number of compounds
1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
1
1
Number of compounds
1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
1
1
Number of compounds
1
phosphoinositide-3-kinase regulatory subunit 2
1
1
Number of compounds
1
Granulocyte macrophage colony-stimulating factor receptor
1
1
Number of compounds
1
signal transducer and activator of transcription 6
1
1
Number of compounds
1
P2X2
1
1
Number of compounds
1
P2X3
1
1
Number of compounds
1
phosphatidylinositol 4-kinase beta
1
1
Number of compounds
1
EBCL-0013