Compound libraries
Products
EBC main page
Search
Impurities
Chemical probes
Contact
Services
© 2026 Copyright Enamine
Back
Bioactive Library II is a collection of 5508 compounds with annotated biological activity. This collection is based on Bioactive Library I and contains compounds with sub-one micromolar activity coefficient values only.
Related terms: GPCR, carbonic anhydrase, ligand-gated ion channel, receptor tyrosine kinase, RTK, nRTK, cytochrome P450, voltage-gated ion channel, oxidoreductase, catecholamine turnover
Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions.
DHP-053 is a blocker of voltage-dependent L-type calcium channel.
TCS 359 is an inhibitor of receptor-type tyrosine-protein kinase FLT3.
AS1842856 is a specific Foxo1 inhibitor, it potently suppresses autophagy.
We propose the complete list of Services powered by Enamine
All our products are for research purpose only. Any personal or non-scientific use is strictly prohibited.
NoteAll the compounds with solubility below 10 mM are shipped as 2 mM solutions.
G protein-coupled receptors
963
963
Number of compounds
963
Carbonic anhydrases
522
522
Number of compounds
522
Ligand-gated ion channels
226
226
Number of compounds
226
Receptor tyrosine kinases (RTKs)
179
179
Number of compounds
179
Cytochrome P450
124
124
Number of compounds
124
Voltage-gated ion channels
107
107
Number of compounds
107
1.-.-.- Oxidoreductases
105
105
Number of compounds
105
Catecholamine turnover
94
94
Number of compounds
94
Non-receptor tyrosine kinases (nRTKs)
90
90
Number of compounds
90
Eicosanoid turnover
88
88
Number of compounds
88
Acetylcholine turnover
84
84
Number of compounds
84
Steroid hormone receptors
84
84
Number of compounds
84
Chromatin modifying enzymes
67
67
Number of compounds
67
Potassium channels
66
66
Number of compounds
66
Hydrolases
64
64
Number of compounds
64
SLC6 neurotransmitter transporter family
63
63
Number of compounds
63
Nuclear hormone receptors
53
53
Number of compounds
53
ATP-binding cassette transporter family
48
48
Number of compounds
48
Endocannabinoid turnover
44
44
Number of compounds
44
Sigma receptors
40
40
Number of compounds
40
MA: Metallo (M) Peptidases
40
40
Number of compounds
40
Poly ADP-ribose polymerases
38
38
Number of compounds
38
SLC superfamily of solute carriers
38
38
Number of compounds
38
L-Arginine turnover
34
34
Number of compounds
34
SLC22 family of organic cation and anion transporters
32
32
Number of compounds
32
PA: Serine (S) Peptidases
32
32
Number of compounds
32
Mitogen-activated protein kinases (MAP kinases)
26
26
Number of compounds
26
Orphan and other 7TM receptors
25
25
Number of compounds
25
Cyclin-dependent kinase (CDK) family
24
24
Number of compounds
24
CAMK: Calcium/calmodulin-dependent protein kinases
23
23
Number of compounds
23
Cyclic nucleotide turnover/signalling
23
23
Number of compounds
23
CAMK-like (CAMKL) family
22
22
Number of compounds
22
MG: Metallo (M) Peptidases
20
20
Number of compounds
20
Aryl hydrocarbon receptor complex
20
20
Number of compounds
20
CMGC: Containing CDK, MAPK, GSK3, CLK families
20
20
Number of compounds
20
CA: Cysteine (C) Peptidases
20
20
Number of compounds
20
Chloride channels
20
20
Number of compounds
20
AGC: Containing PKA, PKG, PKC families
18
18
Number of compounds
18
Glycogen synthase kinase (GSK) family
17
17
Number of compounds
17
Lanosterol biosynthesis pathway
17
17
Number of compounds
17
Catalytic receptors
16
16
Number of compounds
16
SC: Serine (S) Peptidases
15
15
Number of compounds
15
Glycerophospholipid turnover
14
14
Number of compounds
14
CD: Cysteine (C) Peptidases
12
12
Number of compounds
12
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase (DYRK) family
12
12
Number of compounds
12
RAF family
11
11
Number of compounds
11
CK1: Casein kinase 1
11
11
Number of compounds
11
Casein kinase 2 (CK2) family
11
11
Number of compounds
11
E3 ubiquitin ligase components
11
11
Number of compounds
11
STE20 family
10
10
Number of compounds
10
Tubulins
10
10
Number of compounds
10
Protein kinase C (PKC) family
10
10
Number of compounds
10
Receptor serine/threonine kinase (RSTK) family
10
10
Number of compounds
10
1.13.11.- Dioxygenases
9
9
Number of compounds
9
STE: Homologs of yeast Sterile 7, Sterile 11, Sterile 20 kinases
8
8
Number of compounds
8
Heat shock proteins
8
8
Number of compounds
8
Pattern recognition receptors
8
8
Number of compounds
8
Adenosine turnover
7
7
Number of compounds
7
SLC28 and SLC29 families of nucleoside transporters
7
7
Number of compounds
7
Bromodomain-containing proteins
7
7
Number of compounds
7
Ceramide turnover
7
7
Number of compounds
7
Transcription factors
7
7
Number of compounds
7
RSK family
6
6
Number of compounds
6
IKK family
6
6
Number of compounds
6
Interleukin-1 receptor-associated kinase (IRAK) family
6
6
Number of compounds
6
NADPH oxidases
6
6
Number of compounds
6
PB: Threonine (T) Peptidases
6
6
Number of compounds
6
SLC5 family of sodium-dependent glucose transporters
6
6
Number of compounds
6
DMPK family
5
5
Number of compounds
5
NAK family
5
5
Number of compounds
5
MH: Metallo (M) Peptidases
5
5
Number of compounds
5
Carrier proteins
4
4
Number of compounds
4
Aurora kinase (Aur) family
4
4
Number of compounds
4
Numb-associated kinase (NAK) family
4
4
Number of compounds
4
DNA topoisomerases
4
4
Number of compounds
4
Bromodomain kinase (BRDK) family
4
4
Number of compounds
4
CD molecules
4
4
Number of compounds
4
Phosphatidyl inositol 3' kinase-related kinases (PIKK) family
4
4
Number of compounds
4
Leucine-rich repeat kinase (LRRK) family
4
4
Number of compounds
4
SLC2 family of hexose and sugar alcohol transporters
4
4
Number of compounds
4
Viral protein targets
3
3
Number of compounds
3
1.4.3.13 Lysyl oxidases
3
3
Number of compounds
3
2.1.1.- Methyltransferases
3
3
Number of compounds
3
3.2.1.- Glycosidases
3
3
Number of compounds
3
Alpha kinase family
3
3
Number of compounds
3
WEE family
3
3
Number of compounds
3
Fatty acid-binding proteins
3
3
Number of compounds
3
Mixed Lineage Kinase (MLK) family
3
3
Number of compounds
3
IRE family
3
3
Number of compounds
3
LIM domain kinase (LISK) family
3
3
Number of compounds
3
1.14.13.9 Kynurenine 3-monooxygenase
2
2
Number of compounds
2
AA: Aspartic (A) Peptidases
2
2
Number of compounds
2
Adiponectin receptors
2
2
Number of compounds
2
F-type and V-type ATPases
2
2
Number of compounds
2
SLC1 family of amino acid transporters
2
2
Number of compounds
2
Amino acid hydroxylases
2
2
Number of compounds
2
G protein-coupled receptor kinases (GRKs)
2
2
Number of compounds
2
Lipid modifying kinases
2
2
Number of compounds
2
MC: Metallo (M) Peptidases
2
2
Number of compounds
2
RIO family
2
2
Number of compounds
2
Receptor interacting protein kinase (RIPK) family
2
2
Number of compounds
2
NIMA (never in mitosis gene a)- related kinase (NEK) family
2
2
Number of compounds
2
TKL-unique family
2
2
Number of compounds
2
2.3.1.- Acyltransferases
1
1
Number of compounds
1
2.4.2.1 Purine-nucleoside phosphorylase
1
1
Number of compounds
1
TTK family
1
1
Number of compounds
1
CAMKK family
1
1
Number of compounds
1
Cytokine receptor family
1
1
Number of compounds
1
5.2.-.- Cis-trans-isomerases
1
1
Number of compounds
1
G-alpha family G(q) subfamily
1
1
Number of compounds
1
GABA turnover
1
1
Number of compounds
1
Immunoglobulin like domain containing proteins
1
1
Number of compounds
1
Inositol phosphate turnover
1
1
Number of compounds
1
Kelch-like proteins
1
1
Number of compounds
1
MAPK-Activated Protein Kinase (MAPKAPK) family
1
1
Number of compounds
1
MP: Metallo (M) Peptidases
1
1
Number of compounds
1
Hydrogen sulphide synthesis
1
1
Number of compounds
1
Carboxylases and decarboxylases
1
1
Number of compounds
1
Haem oxygenase
1
1
Number of compounds
1
Nucleotide turnover
1
1
Number of compounds
1
P-type ATPases
1
1
Number of compounds
1
P2C P-type ATPases
1
1
Number of compounds
1
Polo-like kinase (PLK) family
1
1
Number of compounds
1
Other ion channels
1
1
Number of compounds
1
SB: Serine (S) Peptidases
1
1
Number of compounds
1
Thyroid hormone turnover
1
1
Number of compounds
1
EBCL-0002