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The U.S. Food and Drug Administration (FDA) is the federal regulatory agency in the United States tasked with ensuring the safety and efficacy of foods, medications, vaccines, medical devices, cosmetics, animal and veterinary products, tobacco products, and devices emitting electromagnetic radiation. Among its critical responsibilities, the FDA oversees the approval process for new drugs before they become available to the public.
The Full Library of FDA approved drugs includes 1708 molecules and represents all medications available for sale by Enamine today.
Related terms: FDA, HCA2 receptor, Kv11.1, Androgen receptor, Acetylcholinesterase, Caspase 3, Pancreatic lipase, D3 receptor.
Indobufen is a platelet aggregation inhibitor. Indobufen is a reversible platelet cyclooxygenase activity inhibitor.
Leflunomide is a pyrimidine synthesis inhibitor, inhibiting dihydroorotate dehydrogenase.
Tofacitinib is an inhibitor of Janus kinases.
This compound shows inhibitory activity against mitogen-activated protein kinase 10.
We propose the complete list of Services powered by Enamine
All our products are for research purpose only. Any personal or non-scientific use is strictly prohibited.
NoteAll the compounds with solubility below 10 mM are shipped as 2 mM solutions.
Carbonic anhydrases
82
82
Number of compounds
82
Oxidoreductases
72
72
Number of compounds
72
Adrenoceptors
63
63
Number of compounds
63
Voltage-gated potassium channels (Kv)
55
55
Number of compounds
55
Others
54
54
Number of compounds
54
Dopamine receptors
52
52
Number of compounds
52
Histamine receptors
47
47
Number of compounds
47
3C. 3-Ketosteroid receptors
45
45
Number of compounds
45
Acetylcholine turnover
43
43
Number of compounds
43
5-Hydroxytryptamine receptors
42
42
Number of compounds
42
S1: Chymotrypsin
32
32
Number of compounds
32
Monoamine transporter subfamily
30
30
Number of compounds
30
3A. Estrogen receptors
29
29
Number of compounds
29
Acetylcholine receptors (muscarinic)
29
29
Number of compounds
29
Ionotropic glutamate receptors
24
24
Number of compounds
24
Histone deacetylases (HDACs)
24
24
Number of compounds
24
Voltage-gated calcium channels (CaV)
24
24
Number of compounds
24
CYP2 family: drug metabolising subset
24
24
Number of compounds
24
Hydrolases
23
23
Number of compounds
23
"CYP11, CYP17, CYP19, CYP20 and CYP21 families"
21
21
Number of compounds
21
"Phosphodiesterases, 3',5'-cyclic nucleotide (PDEs)"
21
21
Number of compounds
21
Transient Receptor Potential channels (TRP)
20
20
Number of compounds
20
Type I RTKs: ErbB (epidermal growth factor) receptor family
18
18
Number of compounds
18
ABCG subfamily
18
18
Number of compounds
18
Janus kinase (JakA) family
16
16
Number of compounds
16
Organic anion transporters (OATs)
16
16
Number of compounds
16
M24: Methionyl aminopeptidase
16
16
Number of compounds
16
Catecholamine turnover
16
16
Number of compounds
16
S9: Prolyl oligopeptidase
15
15
Number of compounds
15
Voltage-gated sodium channels (NaV)
15
15
Number of compounds
15
Nicotinic acetylcholine receptors (nACh)
15
15
Number of compounds
15
Adenosine receptors
14
14
Number of compounds
14
1C. Peroxisome proliferator-activated receptors
14
14
Number of compounds
14
M2: Angiotensin-converting enzymes (ACE and ACE2)
12
12
Number of compounds
12
Chemokine receptors
12
12
Number of compounds
12
SLCO family of organic anion transporting polypeptides
12
12
Number of compounds
12
CYP1 family
12
12
Number of compounds
12
Organic cation transporters (OCT)
11
11
Number of compounds
11
Tubulins
11
11
Number of compounds
11
Heat shock proteins
11
11
Number of compounds
11
Blood coagulation components
11
11
Number of compounds
11
DNA topoisomerases
11
11
Number of compounds
11
Lanosterol biosynthesis pathway
11
11
Number of compounds
11
"Calcium- and sodium-activated potassium channels (KCa, KNa)"
11
11
Number of compounds
11
Angiotensin receptors
10
10
Number of compounds
10
1I. Vitamin D receptor-like receptors
10
10
Number of compounds
10
M28: Aminopeptidase Y
10
10
Number of compounds
10
CYP3 family
10
10
Number of compounds
10
GABAA receptors
10
10
Number of compounds
10
Type IV RTKs: VEGF (vascular endothelial growth factor) receptor family
9
9
Number of compounds
9
Prostanoid receptors
9
9
Number of compounds
9
Inwardly rectifying potassium channels (KIR)
9
9
Number of compounds
9
ABCB subfamily
9
9
Number of compounds
9
Lipoxygenases
9
9
Number of compounds
9
Poly ADP-ribose polymerases
9
9
Number of compounds
9
ABCC subfamily
9
9
Number of compounds
9
Glycosidases
9
9
Number of compounds
9
E3 ubiquitin ligase components
7
7
Number of compounds
7
Aryl hydrocarbon receptor
7
7
Number of compounds
7
M10: Matrix metallopeptidase
7
7
Number of compounds
7
Metabotropic glutamate receptors
7
7
Number of compounds
7
5-HT3 receptors
7
7
Number of compounds
7
Nitric oxide synthases
7
7
Number of compounds
7
Adenosine turnover
7
7
Number of compounds
7
M1: Aminopeptidase N
7
7
Number of compounds
7
Aurora kinase (Aur) family
6
6
Number of compounds
6
T1: Proteasome
6
6
Number of compounds
6
Type II RTKs: Insulin receptor family
6
6
Number of compounds
6
Fatty acid-binding proteins
6
6
Number of compounds
6
Organic zwitterions/cation transporters (OCTN)
6
6
Number of compounds
6
Free fatty acid receptors
6
6
Number of compounds
6
Melatonin receptors
6
6
Number of compounds
6
UDP glucuronosyltransferases (UGT)
6
6
Number of compounds
6
Polo-like kinase (PLK) family
5
5
Number of compounds
5
CLK family
5
5
Number of compounds
5
Vasopressin and oxytocin receptors
5
5
Number of compounds
5
Tachykinin receptors
5
5
Number of compounds
5
"Phosphatidylinositol-4,5-bisphosphate 3-kinase family"
5
5
Number of compounds
5
GSK subfamily
5
5
Number of compounds
5
CFTR
5
5
Number of compounds
5
Prostaglandin synthases
5
5
Number of compounds
5
p38 subfamily
5
5
Number of compounds
5
Integrins
5
5
Number of compounds
5
Melanocortin receptors
5
5
Number of compounds
5
Ryanodine receptors (RyR)
5
5
Number of compounds
5
Src family
5
5
Number of compounds
5
Class A Orphans
5
5
Number of compounds
5
Trace amine receptor
5
5
Number of compounds
5
Histone acetyltransferases (HATs)
3
3
Number of compounds
3
Gonadotrophin-releasing hormone receptors
3
3
Number of compounds
3
RAF family
3
3
Number of compounds
3
Transthyretin
3
3
Number of compounds
3
"CYP24, CYP26 and CYP27 families"
3
3
Number of compounds
3
Tec family
3
3
Number of compounds
3
Lysophospholipid (S1P) receptors
3
3
Number of compounds
3
Isocitrate dehydrogenases
3
3
Number of compounds
3
Type XIV RTKs: RET
3
3
Number of compounds
3
Calcium-sensing receptor
3
3
Number of compounds
3
ERK subfamily
3
3
Number of compounds
3
M13: Neprilysin
3
3
Number of compounds
3
Hexose transporter family
3
3
Number of compounds
3
JNK subfamily
3
3
Number of compounds
3
"CYP39, CYP46 and CYP51 families"
3
3
Number of compounds
3
Bile acid receptor
3
3
Number of compounds
3
Type XIII RTKs: Ephrin receptor family
3
3
Number of compounds
3
Toll-like receptor family
3
3
Number of compounds
3
STAT transcription factors
3
3
Number of compounds
3
Prolyl hydroxylases
3
3
Number of compounds
3
C44: Phosphoribosyl pyrophosphate amidotransferase
3
3
Number of compounds
3
CDK9 subfamily
3
3
Number of compounds
3
SLC29 family
3
3
Number of compounds
3
Acyltransferases
3
3
Number of compounds
3
Type V RTKs: FGF (fibroblast growth factor) receptor family
3
3
Number of compounds
3
Phospholipase A2
3
3
Number of compounds
3
SLC18 family of vesicular amine transporters
3
3
Number of compounds
3
Methyltransferases
3
3
Number of compounds
3
Basic leucine zipper domain TFs
3
3
Number of compounds
3
Hydroxycarboxylic acid receptors
3
3
Number of compounds
3
Nucleotide turnover
3
3
Number of compounds
3
ABCA subfamily
2
2
Number of compounds
2
Leukotriene receptors
2
2
Number of compounds
2
Type XVII RTKs: ROS receptors
2
2
Number of compounds
2
Class Frizzled GPCRs
2
2
Number of compounds
2
Inhibitors of apoptosis (IAP) protein family
2
2
Number of compounds
2
RAS subfamily
2
2
Number of compounds
2
FRAP subfamily
2
2
Number of compounds
2
Type X RTKs: HGF (hepatocyte growth factor) receptor family
2
2
Number of compounds
2
STE7 family
2
2
Number of compounds
2
Cannabinoid receptors
2
2
Number of compounds
2
Peptidyl-prolyl cis/trans isomerases
2
2
Number of compounds
2
Two-pore domain potassium channels (K2P)
2
2
Number of compounds
2
STE11 family
2
2
Number of compounds
2
Death-associated kinase (DAPK) family
2
2
Number of compounds
2
PIM family
2
2
Number of compounds
2
NAK family
2
2
Number of compounds
2
2-Acylglycerol ester turnover
2
2
Number of compounds
2
Lysophospholipid (LPA) receptors
2
2
Number of compounds
2
2B. Retinoid X receptors
2
2
Number of compounds
2
Tumour necrosis factor (TNF) receptor family
2
2
Number of compounds
2
Abl family
2
2
Number of compounds
2
GABA transporter subfamily
2
2
Number of compounds
2
A1: Pepsin
2
2
Number of compounds
2
Hexokinases
2
2
Number of compounds
2
"Type III RTKs: PDGFR, CSFR, Kit, FLT3 receptor family"
2
2
Number of compounds
2
Sigma receptors
2
2
Number of compounds
2
TAIRE subfamily
2
2
Number of compounds
2
Thyroid hormone turnover
2
2
Number of compounds
2
Amino acid hydroxylases
2
2
Number of compounds
2
Bradykinin receptors
2
2
Number of compounds
2
Formylpeptide receptors
2
2
Number of compounds
2
Atypical SLC22B subfamily
2
2
Number of compounds
2
Taste 2 receptors
2
2
Number of compounds
2
SGK family
2
2
Number of compounds
2
Opioid receptors
2
2
Number of compounds
2
Alanine/serine/cysteine transporter subfamily
2
2
Number of compounds
2
Receptor tyrosine phosphatase (RTP) family
2
2
Number of compounds
2
GABAB receptors
2
2
Number of compounds
2
NADPH oxidases
2
2
Number of compounds
2
NOD-like receptor family
2
2
Number of compounds
2
Glycine receptors
2
2
Number of compounds
2
GABA turnover
2
2
Number of compounds
2
M14: Carboxypeptidase A
2
2
Number of compounds
2
Class C Orphans
2
2
Number of compounds
2
SLC7 family
2
2
Number of compounds
2
CDK7 subfamily
1
1
Number of compounds
1
Other PIKK family kinases
1
1
Number of compounds
1
Somatostatin receptors
1
1
Number of compounds
1
Endothelin receptors
1
1
Number of compounds
1
CDK5 subfamily
1
1
Number of compounds
1
Proteinase-activated receptors
1
1
Number of compounds
1
Mitochondrial-associated proteins
1
1
Number of compounds
1
1A. Thyroid hormone receptors
1
1
Number of compounds
1
Ghrelin receptor
1
1
Number of compounds
1
Interleukin-1 receptor-associated kinase (IRAK) family
1
1
Number of compounds
1
Dyrk1 subfamily
1
1
Number of compounds
1
M79: Prenyl protease 2
1
1
Number of compounds
1
"CYP5, CYP7 and CYP8 families"
1
1
Number of compounds
1
Transmembrane guanylyl cyclases
1
1
Number of compounds
1
Receptor interacting protein kinase (RIPK) family
1
1
Number of compounds
1
STE20 subfamily
1
1
Number of compounds
1
P2Y receptors
1
1
Number of compounds
1
MSK subfamily
1
1
Number of compounds
1
"Akt (Protein kinase B, PKB) family"
1
1
Number of compounds
1
CRK7 subfamily
1
1
Number of compounds
1
3B. Estrogen-related receptors
1
1
Number of compounds
1
SLC65 NPC-type cholesterol transporters
1
1
Number of compounds
1
ClC family
1
1
Number of compounds
1
P2X receptors
1
1
Number of compounds
1
Decarboxylases
1
1
Number of compounds
1
Neuropeptide Y receptors
1
1
Number of compounds
1
CatSper and Two-Pore channels (TPC)
1
1
Number of compounds
1
"GPR18, GPR55 and GPR119"
1
1
Number of compounds
1
Glucagon receptor family
1
1
Number of compounds
1
Ceramide glucosyltransferase
1
1
Number of compounds
1
Class I transporters
1
1
Number of compounds
1
SLC46 family of folate transporters
1
1
Number of compounds
1
Motilin receptor
1
1
Number of compounds
1
1-phosphatidylinositol 4-kinase family
1
1
Number of compounds
1
M12: Astacin/Adamalysin
1
1
Number of compounds
1
Neuropeptide FF/neuropeptide AF receptors
1
1
Number of compounds
1
Type XII RTKs: TIE family of angiopoietin receptors
1
1
Number of compounds
1
MKN subfamily
1
1
Number of compounds
1
Tau tubulin kinase (TTBK) family
1
1
Number of compounds
1
P2A P-type ATPases: Ca2+-ATPases
1
1
Number of compounds
1
CDK1 subfamily
1
1
Number of compounds
1
C48: Ulp1 endopeptidase
1
1
Number of compounds
1
Relaxin family peptide receptors
1
1
Number of compounds
1
Type I receptor serine/threonine kinases
1
1
Number of compounds
1
SLC47 family of multidrug and toxin extrusion transporters
1
1
Number of compounds
1
Adiponectin receptors
1
1
Number of compounds
1
N-Acylethanolamine turnover
1
1
Number of compounds
1
Carboxylases
1
1
Number of compounds
1
Leukotriene and lipoxin metabolism
1
1
Number of compounds
1
Galanin receptors
1
1
Number of compounds
1
Syk family
1
1
Number of compounds
1
Dioxygenases
1
1
Number of compounds
1
Histone methyltransferases (HMTs)
1
1
Number of compounds
1
C1: Papain
1
1
Number of compounds
1
Iota subfamily
1
1
Number of compounds
1
Purine-nucleoside phosphorylase
1
1
Number of compounds
1
Lysyl oxidases
1
1
Number of compounds
1
Rho kinase
1
1
Number of compounds
1
C2: Calpain
1
1
Number of compounds
1
Pyruvate kinases (EC 2.7.1.40)
1
1
Number of compounds
1
S28: Lysosomal Pro-Xaa carboxypeptidase
1
1
Number of compounds
1
Non-enzymatic BRD containing proteins
1
1
Number of compounds
1
IRE family
1
1
Number of compounds
1
SLC3 family
1
1
Number of compounds
1
AMPK subfamily
1
1
Number of compounds
1
SLC16 family of monocarboxylate transporters
1
1
Number of compounds
1
Pyrimidine salvage
1
1
Number of compounds
1
Mitochondrial uncoupling proteins
1
1
Number of compounds
1
Succinate receptor
1
1
Number of compounds
1
B-cell lymphoma 2 (Bcl-2) protein family
1
1
Number of compounds
1
Arginase
1
1
Number of compounds
1
PDHK family
1
1
Number of compounds
1
Glycine transporter subfamily
1
1
Number of compounds
1
Platelet-activating factor receptor
1
1
Number of compounds
1
Choline transporter
1
1
Number of compounds
1
EBCL-0047